Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2XVD

ephB4 kinase domain inhibitor complex

Summary for 2XVD
Entry DOI10.2210/pdb2xvd/pdb
Related2BBA 2VWU 2VWV 2VWW 2VWX 2VWY 2VWZ 2VX0 2VX1 2X9F
DescriptorEPHRIN TYPE-B RECEPTOR 4, {4-METHYL-3-[(1-METHYLETHYL)(2-{[3-(METHYLSULFONYL)-5-MORPHOLIN-4-YLPHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENYL}METHANOL, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordstransferase, nucleotide-binding
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight34519.37
Authors
Read, J.,Brassington, C.A.,Green, I.,McCall, E.J.,Valentine, A.L. (deposition date: 2010-10-25, release date: 2011-06-08, Last modification date: 2023-12-20)
Primary citationBarlaam, B.,Ducray, R.,Lambert-Van Der Brempt, C.,Ple, P.,Bardelle, C.,Brooks, N.,Coleman, T.,Cross, D.,Kettle, J.G.,Read, J.
Inhibitors of the Tyrosine Kinase Ephb4. Part 4: Discovery and Optimization of a Benzylic Alcohol Series.
Bioorg.Med.Chem.Lett., 21:2207-, 2011
Cited by
PubMed: 21441027
DOI: 10.1016/J.BMCL.2011.03.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon