5TBD

Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222

Summary for 5TBD

Entry DOI	10.2210/pdb5tbd/pdb
Descriptor	Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2, ... (4 entities in total)
Functional Keywords	immunoglobulin fold, immune system, c-terminal msp2, unstructured antigen
Biological source	Mus musculus More
Total number of polymer chains	12
Total formula weight	101886.22
Authors	Seow, J.,Morales, R.A.V.,MacRaild, C.A.,Bankala, K.,Drinkwater, N.,Dingjan, T.,Jaipuria, G.,Wilde, K.,Anders, R.F.,Atreya, H.S.,Christ, D.,McGowan, S.,Norton, R.S. (deposition date: 2016-09-12, release date: 2017-02-15, Last modification date: 2023-10-04)
Primary citation	Seow, J.,Morales, R.A.,MacRaild, C.A.,Krishnarjuna, B.,McGowan, S.,Dingjan, T.,Jaipuria, G.,Rouet, R.,Wilde, K.L.,Atreya, H.S.,Richards, J.S.,Anders, R.F.,Christ, D.,Drinkwater, N.,Norton, R.S. Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2. J. Mol. Biol., 429:836-846, 2017 Cited by PubMed: 28189425 DOI: 10.1016/j.jmb.2017.02.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation