5BRY
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![BU of 5bry by Molmil](/molmil-images/mine/5bry) | HIV-1 wild Type protease with GRL-011-11A (a methylamine bis-Tetrahydrofuran P2-Ligand, sulfonamide isostere derivate) | 分子名称: | (3R,3aS,4R,6aR)-4-(methylamino)hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, Protease, ... | 著者 | Wang, Y.-F, Agniswamy, J, Weber, I.T. | 登録日 | 2015-06-01 | 公開日 | 2015-09-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Design of HIV-1 Protease Inhibitors with Amino-bis-tetrahydrofuran Derivatives as P2-Ligands to Enhance Backbone-Binding Interactions: Synthesis, Biological Evaluation, and Protein-Ligand X-ray Studies. J.Med.Chem., 58, 2015
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7LTW
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![BU of 7ltw by Molmil](/molmil-images/mine/7ltw) | Crystal structure of the mouse Kirrel2 D1 homodimer | 分子名称: | Kin of IRRE-like protein 2, SODIUM ION | 著者 | Roman, C.A, Pak, J.S, Wang, J, Ozkan, E. | 登録日 | 2021-02-20 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep, 37, 2021
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1L4W
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![BU of 1l4w by Molmil](/molmil-images/mine/1l4w) | NMR structure of an AChR-peptide (Torpedo Californica, alpha-subunit residues 182-202) in complex with alpha-Bungarotoxin | 分子名称: | Acetylcholine receptor protein, alpha-Bungarotoxin | 著者 | Samson, A.O, Scherf, T, Rodriguez, E, Eisenstein, M, Anglister, J. | 登録日 | 2002-03-06 | 公開日 | 2002-07-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | The mechanism for acetylcholine receptor inhibition by alpha-neurotoxins and species-specific resistance to alpha-bungarotoxin revealed by NMR. Neuron, 35, 2002
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2Z6J
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![BU of 2z6j by Molmil](/molmil-images/mine/2z6j) | Crystal Structure of S. pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID, CALCIUM ION, ... | 著者 | Saito, J, Yamada, M, Watanabe, T, Takeuchi, Y. | 登録日 | 2007-08-01 | 公開日 | 2008-04-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor. Protein Sci., 17, 2008
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8OEP
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![BU of 8oep by Molmil](/molmil-images/mine/8oep) | Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide | 分子名称: | Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 | 著者 | Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. | 登録日 | 2023-03-11 | 公開日 | 2023-05-10 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
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7LR3
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![BU of 7lr3 by Molmil](/molmil-images/mine/7lr3) | Complex of Fab 2/6.14 with domain 3 of P. berghei HAP2 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D3_2/6.14 Fab heavy chain, D3_2/6.14 Fab light chain, ... | 著者 | Feng, J, Dong, X.C, Lu, C.F, Springer, T.A. | 登録日 | 2021-02-15 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2. Elife, 10, 2021
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2ZKW
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![BU of 2zkw by Molmil](/molmil-images/mine/2zkw) | Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21 | 分子名称: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Yoshikawa, S, Kukimoto-Niino, M, Ito, K, Chen, L, Fu, Z.Q, Chrzas, J, Wang, B.C, Shirouzu, M, Urushitani, M, Takahashi, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2008-03-31 | 公開日 | 2009-03-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21 To be Published
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5KDD
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![BU of 5kdd by Molmil](/molmil-images/mine/5kdd) | Apo-structure of humanised RadA-mutant humRadA22 | 分子名称: | DNA repair and recombination protein RadA, SULFATE ION | 著者 | Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. | 登録日 | 2016-06-08 | 公開日 | 2016-10-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
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1GUB
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![BU of 1gub by Molmil](/molmil-images/mine/1gub) | Hinge-bending motion of D-allose binding protein from Escherichia coli: three open conformations | 分子名称: | D-ALLOSE-BINDING PERIPLASMIC PROTEIN, NICKEL (II) ION | 著者 | Magnusson, U, Chaudhuri, B.N, Ko, J, Park, C, Jones, T.A, Mowbray, S.L. | 登録日 | 2002-01-24 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of D-Allose Binding Protein from Escherichia Coli Bound to D-Allose at 1.8 A Resolution J.Mol.Biol., 286, 1999
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7LR4
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![BU of 7lr4 by Molmil](/molmil-images/mine/7lr4) | Complex of Fab 2/1.12 with domain 3 of P. berghei HAP2 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, D3_2/1.12 Fab heavy chain, D3_2/1.12 Fab light chain, ... | 著者 | Feng, J, Dong, X.C, Su, Y, Lu, X.F, Springer, T.A. | 登録日 | 2021-02-15 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2. Elife, 10, 2021
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5AXL
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![BU of 5axl by Molmil](/molmil-images/mine/5axl) | Crystal structure of Thg1 like protein (TLP) with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA(His)-5'-guanylyltransferase (Thg1) like protein | 著者 | Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. | 登録日 | 2015-07-31 | 公開日 | 2016-08-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | 主引用文献 | Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
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7LKY
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5KEN
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![BU of 5ken by Molmil](/molmil-images/mine/5ken) | EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ebola surface glycoprotein, ... | 著者 | Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B. | 登録日 | 2016-06-09 | 公開日 | 2016-09-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nat Microbiol, 1, 2016
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5AMR
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![BU of 5amr by Molmil](/molmil-images/mine/5amr) | |
4O81
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![BU of 4o81 by Molmil](/molmil-images/mine/4o81) | |
5AUM
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1GUD
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![BU of 1gud by Molmil](/molmil-images/mine/1gud) | Hinge-bending motion of D-allose binding protein from Escherichia coli: three open conformations | 分子名称: | D-ALLOSE-BINDING PERIPLASMIC PROTEIN, ZINC ION | 著者 | Magnusson, U, Chaudhuri, B.N, Ko, J, Park, C, Jones, T.A, Mowbray, S.L. | 登録日 | 2002-01-24 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure of D-Allose Binding Protein from Escherichia Coli Bound to D-Allose at 1.8 A Resolution J.Mol.Biol., 286, 1999
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5B5X
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![BU of 5b5x by Molmil](/molmil-images/mine/5b5x) | Crystal structure of limiting CO2-inducible protein LCIC | 分子名称: | SULFATE ION, ZINC ION, limiting CO2-inducible protein LCIC | 著者 | Jin, S, Sun, J, Wunder, T, Tang, D, Mueller-Cajar, O.M, Gao, Y. | 登録日 | 2016-05-24 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.511 Å) | 主引用文献 | Structural insights into the LCIB protein family reveals a new group of beta-carbonic anhydrases Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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1RVI
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![BU of 1rvi by Molmil](/molmil-images/mine/1rvi) | SOLUTION STRUCTURE OF THE DNA DODECAMER CGTTTTAAAACG | 分子名称: | 5'-D(*CP*GP*TP*TP*TP*TP*AP*AP*AP*AP*CP*G)-3' | 著者 | Stefl, R, Wu, H, Ravindranathan, S, Sklenar, V, Feigon, J. | 登録日 | 2003-12-13 | 公開日 | 2004-02-10 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | DNA A-tract bending in three dimensions: Solving the dA4T4 vs. dT4A4 conundrum. Proc.Natl.Acad.Sci.USA, 101, 2004
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7L8K
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![BU of 7l8k by Molmil](/molmil-images/mine/7l8k) | Crystal structure of human GPX4-U46C | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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7L8Q
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![BU of 7l8q by Molmil](/molmil-images/mine/7l8q) | Crystal structure of human GPX4-U46C with oxidized Cys-46 | 分子名称: | ACETATE ION, Phospholipid hydroperoxide glutathione peroxidase | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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5KEQ
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![BU of 5keq by Molmil](/molmil-images/mine/5keq) | High resolution cryo-EM maps of Human papillomavirus 16 reveal L2 location and heparin-induced conformational changes | 分子名称: | Major capsid protein L1 | 著者 | Guan, J, Bywaters, S.M, Brendle, S.A, Ashley, R.E, Makhov, A.M, Conway, J.F, Christensen, N.D, Hafenstein, S. | 登録日 | 2016-06-10 | 公開日 | 2017-01-25 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site. Structure, 25, 2017
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2ZFU
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![BU of 2zfu by Molmil](/molmil-images/mine/2zfu) | Structure of the methyltransferase-like domain of nucleomethylin | 分子名称: | Cerebral protein 1, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Minami, H, Hashimoto, H, Murayama, A, Yanagisawa, J, Sato, M, Shimizu, T. | 登録日 | 2008-01-14 | 公開日 | 2008-12-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Epigenetic control of rDNA loci in response to intracellular energy status Cell(Cambridge,Mass.), 133, 2008
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1LD6
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![BU of 1ld6 by Molmil](/molmil-images/mine/1ld6) | STRUCTURE OF BPTI_8A MUTANT | 分子名称: | PANCREATIC TRYPSIN INHIBITOR | 著者 | Cierpicki, T, Otlewski, J. | 登録日 | 2002-04-08 | 公開日 | 2002-09-11 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability. J.Mol.Biol., 321, 2002
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4OA4
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![BU of 4oa4 by Molmil](/molmil-images/mine/4oa4) | CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM SHEWANELLA LOIHICA PV-4 (Shew_1446), TARGET EFI-510273, WITH BOUND SUCCINATE | 分子名称: | CHLORIDE ION, SUCCINIC ACID, TRAP dicarboxylate transporter, ... | 著者 | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-01-03 | 公開日 | 2014-02-05 | 最終更新日 | 2015-02-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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