8OEP
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
Summary for 8OEP
Entry DOI | 10.2210/pdb8oep/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 3, Protein E6, SODIUM ION, ... (4 entities in total) |
Functional Keywords | protein tyrosine phosphatase ptpn3, pdz domains, pdz-binding motif, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 28961.46 |
Authors | Genera, M.,Colcombet-Cazenave, B.,Croitoru, A.,Raynal, B.,Mechaly, A.,Caillet, J.,Haouz, A.,Wolff, N.,Caillet-Saguy, C. (deposition date: 2023-03-11, release date: 2023-05-10, Last modification date: 2023-05-31) |
Primary citation | Genera, M.,Colcombet-Cazenave, B.,Croitoru, A.,Raynal, B.,Mechaly, A.,Caillet, J.,Haouz, A.,Wolff, N.,Caillet-Saguy, C. Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10:1192621-1192621, 2023 Cited by PubMed: 37200868DOI: 10.3389/fmolb.2023.1192621 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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