8OEP
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tyrosine-protein phosphatase non-receptor type 3 | polymer | 114 | 12709.2 | 2 | UniProt (P26045) Pfam (PF00595) | Homo sapiens (human) | Protein-tyrosine phosphatase H1,PTP-H1 |
| 2 | B, D (B, D) | Protein E6 | polymer | 13 | 1760.0 | 2 | UniProt (P06463) | human papillomavirus 18 | |
| 3 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, C: -11 - 97 (UniProt: P26045)
| PDB | External Database | Details |
|---|---|---|
| Gly -16 | - | expression tag |
| Ala -15 | - | expression tag |
| Met -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Ser -12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 28938.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 28961.5 |
