7LR3

Complex of Fab 2/6.14 with domain 3 of P. berghei HAP2

Summary for 7LR3

Entry DOI	10.2210/pdb7lr3/pdb
Descriptor	D3_2/6.14 Fab light chain, D3_2/6.14 Fab heavy chain, Hapless 2, ... (7 entities in total)
Functional Keywords	transmission-blocking malaria vaccine, membrane fusion, gamete fusogen, monoclonal antibody, surfactant protein, surfactant protein-immune system complex, surfactant protein/immune system
Biological source	Mus musculus More
Total number of polymer chains	6
Total formula weight	124454.88
Authors	Feng, J.,Dong, X.C.,Lu, C.F.,Springer, T.A. (deposition date: 2021-02-15, release date: 2021-12-15, Last modification date: 2023-10-18)
Primary citation	Feng, J.,Dong, X.,DeCosta, A.,Su, Y.,Angrisano, F.,Sala, K.A.,Blagborough, A.M.,Lu, C.,Springer, T.A. Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2. Elife, 10:-, 2021 Cited by PubMed: 34939934 DOI: 10.7554/eLife.74707 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation