7LR4

Complex of Fab 2/1.12 with domain 3 of P. berghei HAP2

Summary for 7LR4

• Entry DOI: 10.2210/pdb7lr4/pdb
• Descriptor: D3_2/1.12 Fab heavy chain, D3_2/1.12 Fab light chain, Hapless 2, ... (6 entities in total)
• Functional Keywords: transmission-blocking malaria vaccine, membrane fusion, gamete fusogen, monoclonal antibody, surfactant protein, cell adhesion, cell adhesion-immune system complex, cell adhesion/immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 124413.22

Authors

Feng, J.,Dong, X.C.,Su, Y.,Lu, X.F.,Springer, T.A. (deposition date: 2021-02-15, release date: 2021-12-15, Last modification date: 2023-10-18)

• Primary citation: Feng, J.,Dong, X.,DeCosta, A.,Su, Y.,Angrisano, F.,Sala, K.A.,Blagborough, A.M.,Lu, C.,Springer, T.A.; Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2.; Elife, 10:-, 2021; PubMed: 34939934; DOI: 10.7554/eLife.74707

Experimental method

X-RAY DIFFRACTION (2.1 Å)