5KEN

EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6

Summary for 5KEN

• Entry DOI: 10.2210/pdb5ken/pdb
• Related: 5KEL 5KEM
• EMDB information: 8240 8241 8242
• Descriptor: Ebola surface glycoprotein, GP1, Ebola surface glycoprotein, GP2, c4G7 variable Fab domain heavy chain, ... (9 entities in total)
• Functional Keywords: ebola virus surface glycoprotein, therapeutic antibody cocktail, zmapp, viral protein-immune system complex, viral protein/immune system
• Biological source: Zaire ebolavirus (ZEBOV); More
• Total number of polymer chains: 16
• Total formula weight: 258668.40

Authors

Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe Jr., J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B. (deposition date: 2016-06-09, release date: 2016-09-07, Last modification date: 2020-07-29)

• Primary citation: Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe, J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B.; Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.; Nat Microbiol, 1:16128-16128, 2016; PubMed: 27562261; DOI: 10.1038/nmicrobiol.2016.128

Experimental method

ELECTRON MICROSCOPY (4.3 Å)