5KEL
EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6
Summary for 5KEL
Entry DOI | 10.2210/pdb5kel/pdb |
Related | 5KEM 5KEN |
EMDB information | 8240 8241 8242 |
Descriptor | Ebola surface glycoprotein, GP1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | ebola virus surface glycoprotein, therapeutic antibody cocktail, zmapp, viral protein-immune system complex, viral protein/immune system |
Biological source | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) More |
Total number of polymer chains | 18 |
Total formula weight | 359998.05 |
Authors | Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe Jr., J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B. (deposition date: 2016-06-09, release date: 2016-09-07, Last modification date: 2020-07-29) |
Primary citation | Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe, J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B. Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nat Microbiol, 1:16128-16128, 2016 Cited by PubMed: 27562261DOI: 10.1038/nmicrobiol.2016.128 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
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