5KEL
EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, M (A, E, F) | Ebola surface glycoprotein, GP1 | polymer | 469 | 50974.0 | 3 | UniProt (Q05320) Pfam (PF01611) | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) | |
| 2 | B, H, N (B, G, I) | Ebola surface glycoprotein, GP2 | polymer | 143 | 16137.1 | 3 | UniProt (Q05320) Pfam (PF22307) | Zaire ebolavirus (ZEBOV) | |
| 3 | C, I, O (H, P, Q) | c2G4 variable Fab domain heavy chain | polymer | 120 | 13573.1 | 3 | Homo sapiens (human) | ||
| 4 | D, J, P (L, T, U) | c2G4 variable Fab domain light chain | polymer | 107 | 11641.9 | 3 | Homo sapiens (human) | ||
| 5 | E, K, Q (C, J, M) | c13C6 variable Fab domain heavy chain | polymer | 121 | 13169.7 | 3 | Homo sapiens (human) | ||
| 6 | F, L, R (D, N, O) | c13C6 variable Fab domain light chain | polymer | 107 | 11611.9 | 3 | Homo sapiens (human) | ||
| 7 | AA, S, W (a, K, W) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 8 | BA, T, X (b, R, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 9 | CA, U, Y (c, S, Y) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 10 | DA, V, Z (d, V, Z) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 11 | EA, FA, GA (A, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
B, G, I: 502 - 637 (UniProt: Q05320)
| PDB | External Database | Details |
|---|---|---|
| Thr 544 | Ile 544 | conflict |
| Leu 638 | - | expression tag |
| Glu 639 | - | expression tag |
| Val 640 | - | expression tag |
| Asp 641 | - | expression tag |
| Asp 642 | - | expression tag |
| Asp 643 | - | expression tag |
| Asp 644 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 351323.1 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 8011.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 359998.1 |
