5KEN

EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, K (A, E, K)	Ebola surface glycoprotein, GP1	polymer	276	30910.7	3	UniProt (Q05320) Pfam (PF01611)	Zaire ebolavirus (ZEBOV)
2	B, F, L (B, F, M)	Ebola surface glycoprotein, GP2	polymer	113	12650.4	3	UniProt (Q05320) Pfam (PF22307)	Zaire ebolavirus (strain Mayinga-76) (ZEBOV)
3	C, G, M (C, G, N)	c4G7 variable Fab domain heavy chain	polymer	118	12851.2	3		Homo sapiens (human)
4	D, H, N (D, H, O)	c4G7 variable Fab domain light chain	polymer	107	11733.0	3		Homo sapiens (human)
5	I, O (I, P)	c13C6 variable Fab domain light chain	polymer	107	11611.9	2		Homo sapiens (human)
6	J, P (J, Q)	c13C6 variable Fab domain heavy chain	polymer	121	13169.7	2		Homo sapiens (human)
7	Q, S, T (L, S, T)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G22768VO)
8	R, U, V (R, U, V)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
9	W, X, Y (E, K)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

B, F, M: 503 - 615 (UniProt: Q05320)

PDB	External Database	Details
Thr 544	Ile 544	conflict

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	253999.1
Branched	Number of molecules	6
	Total formula weight	4005.7
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	258668.4

*Water molecules are not included.