3E9G
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![BU of 3e9g by Molmil](/molmil-images/mine/3e9g) | Crystal structure long-form (residue1-124) of Eaf3 chromo domain | 分子名称: | Chromatin modification-related protein EAF3 | 著者 | Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J. | 登録日 | 2008-08-22 | 公開日 | 2008-11-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36 J.Biol.Chem., 283, 2008
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7N27
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![BU of 7n27 by Molmil](/molmil-images/mine/7n27) | Crystal Structure of chromodomain of CDYL in complex with inhibitor UNC6261 | 分子名称: | Isoform 2 of Chromodomain Y-like protein, SODIUM ION, UNKNOWN ATOM OR ION, ... | 著者 | Beldar, S, Dong, A, Loppnau, P, Min, J, Arrowsmith, C.H, Edwards, A.M, Structural Genomics Consortium (SGC) | 登録日 | 2021-05-28 | 公開日 | 2021-07-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of chromodomain of CDYL in complex with inhibitor UNC6261 To Be Published
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3I85
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7MYY
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![BU of 7myy by Molmil](/molmil-images/mine/7myy) | Crystal Structure of HIV-1 PRS17 with GRL-142 | 分子名称: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, CHLORIDE ION, GLYCEROL, ... | 著者 | Agniswamy, J, Weber, I.T. | 登録日 | 2021-05-22 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PR S17 . Biochem.Biophys.Res.Commun., 566, 2021
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5EYT
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![BU of 5eyt by Molmil](/molmil-images/mine/5eyt) | Crystal Structure of Adenylosuccinate Lyase from Schistosoma mansoni in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase | 著者 | Romanello, L, Torini, J.R, Bird, L, Nettleship, J, Owens, R, Reddivari, Y, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2015-11-25 | 公開日 | 2016-11-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3649 Å) | 主引用文献 | Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL). Mol. Biochem. Parasitol., 214, 2017
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4D4Y
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6A7H
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![BU of 6a7h by Molmil](/molmil-images/mine/6a7h) | Bacterial protein toxins | 分子名称: | RTX toxin, SULFATE ION | 著者 | Kim, M.H, Hwang, J, Jang, S.Y. | 登録日 | 2018-07-03 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogenVibrio vulnificus J. Biol. Chem., 293, 2018
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7MYP
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![BU of 7myp by Molmil](/molmil-images/mine/7myp) | Crystal Structure of HIV-1 PRS17 with GRL-44-10A | 分子名称: | (3R,3aS,4R,6aR)-4-methoxyhexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, GLYCEROL, ... | 著者 | Agniswamy, J, Weber, I.T. | 登録日 | 2021-05-21 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PR S17 . Biochem.Biophys.Res.Commun., 566, 2021
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2MZJ
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3EQE
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![BU of 3eqe by Molmil](/molmil-images/mine/3eqe) | Crystal structure of the YubC protein from Bacillus subtilis. Northeast Structural Genomics Consortium target SR112. | 分子名称: | FE (III) ION, Putative cystein dioxygenase | 著者 | Vorobiev, S.M, Su, M, Seetharaman, J, Benach, J, Forouhar, F, Clayton, G, Cooper, B, Wang, H, Foote, E.L, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-09-30 | 公開日 | 2008-10-14 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Crystal structure of the YubC protein from Bacillus subtilis. To be Published
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7N98
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![BU of 7n98 by Molmil](/molmil-images/mine/7n98) | Cryo-EM structure of MFSD2A | 分子名称: | Sodium-dependent lysophosphatidylcholine symporter 1 | 著者 | Zhang, J, Feng, L. | 登録日 | 2021-06-17 | 公開日 | 2021-08-04 | 最終更新日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A. Nature, 596, 2021
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7DDE
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![BU of 7dde by Molmil](/molmil-images/mine/7dde) | Cryo-EM structure of the Ape4 and Nbr1 complex | 分子名称: | Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | 著者 | Zhang, J, Ye, K. | 登録日 | 2020-10-28 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1. Embo J., 40, 2021
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7DD9
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![BU of 7dd9 by Molmil](/molmil-images/mine/7dd9) | Cryo-EM structure of the Ams1 and Nbr1 complex | 分子名称: | Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | 著者 | Zhang, J, Ye, K. | 登録日 | 2020-10-28 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1. Embo J., 40, 2021
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7NJ0
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![BU of 7nj0 by Molmil](/molmil-images/mine/7nj0) | CryoEM structure of the human Separase-Cdk1-cyclin B1-Cks1 complex | 分子名称: | Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 1, G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin-B1, ... | 著者 | Yu, J, Raia, P, Ghent, C.M, Raisch, T, Sadian, Y, Barford, D, Raunser, S, Morgan, D.O, Boland, A. | 登録日 | 2021-02-14 | 公開日 | 2021-08-04 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of human separase regulation by securin and CDK1-cyclin B1. Nature, 596, 2021
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7NJ1
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![BU of 7nj1 by Molmil](/molmil-images/mine/7nj1) | CryoEM structure of the human Separase-Securin complex | 分子名称: | Securin, Separin | 著者 | Yu, J, Raia, P, Ghent, C.M, Raisch, T, Sadian, Y, Barford, D, Raunser, S, Morgan, D.O, Boland, A. | 登録日 | 2021-02-14 | 公開日 | 2021-08-04 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of human separase regulation by securin and CDK1-cyclin B1. Nature, 596, 2021
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2N1R
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![BU of 2n1r by Molmil](/molmil-images/mine/2n1r) | NMR Structure of the Myristylated Feline Immunodeficiency Virus Matrix Protein | 分子名称: | Matrix protein p15 | 著者 | Brown, L.A, Cox, C, Button, R.J, Baptiste, J, Bahlow, K, Spurrier, V, Luttge, B.G, Kuo, L, Freed, E.O, Summers, M.F, Kyser, J, Summers, H.R. | 登録日 | 2015-04-15 | 公開日 | 2015-05-27 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the myristylated feline immunodeficiency virus matrix protein. Viruses, 7, 2015
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3W21
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![BU of 3w21 by Molmil](/molmil-images/mine/3w21) | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase in complex with alpha-KG from Burkholderia ambifaria AMMD | 分子名称: | 2-OXOGLUTARIC ACID, Putative uncharacterized protein, ZINC ION | 著者 | Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. | 登録日 | 2012-11-26 | 公開日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD Plos One, 8, 2013
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2LZE
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![BU of 2lze by Molmil](/molmil-images/mine/2lze) | Ligase 10C | 分子名称: | ZINC ION, a primordial catalytic fold generated by in vitro evolution | 著者 | Chao, F, Morelli, A, Haugner, J, Churchfield, L, Hagmann, L, Shi, L, Masterson, L, Sarangi, R, Veglia, G, Seelig, B. | 登録日 | 2012-10-01 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and dynamics of a primordial catalytic fold generated by in vitro evolution. Nat.Chem.Biol., 9, 2013
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7NNU
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![BU of 7nnu by Molmil](/molmil-images/mine/7nnu) | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs | 分子名称: | Conserved hypothetical membrane protein, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ... | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2021-02-25 | 公開日 | 2021-08-18 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM. Proc.Natl.Acad.Sci.USA, 118, 2021
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1TDE
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![BU of 1tde by Molmil](/molmil-images/mine/1tde) | CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOREDOXIN REDUCTASE REFINED AT 2 ANGSTROM RESOLUTION: IMPLICATIONS FOR A LARGE CONFORMATIONAL CHANGE DURING CATALYSIS | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, THIOREDOXIN REDUCTASE | 著者 | Waksman, G, Krishna, T.S.R, Williams Junior, C.H, Kuriyan, J. | 登録日 | 1994-01-14 | 公開日 | 1994-11-30 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis. J.Mol.Biol., 236, 1994
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4D26
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![BU of 4d26 by Molmil](/molmil-images/mine/4d26) | Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA,ADP and Pi | 分子名称: | 5'-R(*UP*GP*AP*CP*AP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, BMVLG PROTEIN, ... | 著者 | Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S. | 登録日 | 2014-05-07 | 公開日 | 2014-06-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts. Cell(Cambridge,Mass.), 157, 2014
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7NNT
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![BU of 7nnt by Molmil](/molmil-images/mine/7nnt) | Cryo-EM structure of the folate-specific ECF transporter complex in DDM micelles | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2021-02-25 | 公開日 | 2021-08-18 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM. Proc.Natl.Acad.Sci.USA, 118, 2021
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1TGT
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![BU of 1tgt by Molmil](/molmil-images/mine/1tgt) | ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY | 分子名称: | CALCIUM ION, METHANOL, TRYPSINOGEN | 著者 | Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R. | 登録日 | 1981-10-26 | 公開日 | 1982-03-04 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography Acta Crystallogr.,Sect.B, 38, 1982
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3VFS
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![BU of 3vfs by Molmil](/molmil-images/mine/3vfs) | crystal structure of HLA B*3508LPEP-P5Ala , peptide mutant P5-ala | 分子名称: | Beta-2-microglobulin, LPEP peptide from EBV, P5A, ... | 著者 | Liu, Y.C, Rossjohn, J, Gras, S. | 登録日 | 2012-01-10 | 公開日 | 2012-02-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule. J.Biol.Chem., 287, 2012
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4CPX
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![BU of 4cpx by Molmil](/molmil-images/mine/4cpx) | Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol | 分子名称: | CHLORIDE ION, PROTEASE, methyl ~{N}-[(2~{S})-3,3-dimethyl-1-[2-[3-[(3~{R},6~{S},10~{Z})-3-oxidanyl-4,7-bis(oxidanylidene)-6-propan-2-yl-5,8-diazabicyclo[11.2.2]heptadeca-1(16),10,13(17),14-tetraen-3-yl]propyl]-2-[(4-thiophen-2-ylphenyl)methyl]hydrazinyl]-1-oxidanylidene-butan-2-yl]carbamate | 著者 | DeRosa, M, Unge, J, Motwani, H.V, Rosenquist, A, Vrang, L, Wallberg, H, Larhed, M. | 登録日 | 2014-02-08 | 公開日 | 2014-12-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Synthesis of P1'-functionalized macrocyclic transition-state mimicking HIV-1 protease inhibitors encompassing a tertiary alcohol. J. Med. Chem., 57, 2014
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