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PDB: 42254 件

8GRB
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Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isoform A of Isocitrate dehydrogenase [NAD] subunit beta
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-01
公開日2022-12-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GV5
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Crystal structure of PN-SIA28 in complex with influenza hemagglutinin A/swine/Guangdong/104/2013 (H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
著者Chen, Y, Song, H, Qi, J, Gao, G.F.
登録日2022-09-14
公開日2022-12-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
4CKH
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BU of 4ckh by Molmil
Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy
分子名称: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1
著者Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F.
登録日2014-01-06
公開日2014-10-15
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
5G2O
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BU of 5g2o by Molmil
Yersinia pestis FabV variant T276A
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, Enoyl-[acyl-carrier-protein] reductase [NADH]
著者Pschibul, A, Kuper, J, HIrschbeck, M, Kisker, C.
登録日2016-04-11
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia Pestis Fabv Enoyl-Acp Reductase.
Biochemistry, 55, 2016
4CXH
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Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement
分子名称: 18S RRNA - H44, 18S RRNA - H5-H14, 18S RRNA - H8, ...
著者Budkevich, T.V, Giesebrecht, J, Behrmann, E, Loerke, J, Ramrath, D.J.F, Mielke, T, Ismer, J, Hildebrand, P, Tung, C.-S, Nierhaus, K.H, Sanbonmatsu, K.Y, Spahn, C.M.T.
登録日2014-04-07
公開日2014-07-16
最終更新日2019-06-26
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
3ZJ8
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Crystal structure of strictosidine glucosidase in complex with inhibitor-2
分子名称: (1R,2S,3S,4R,5R)-4-[(4-bromophenyl)methylamino]-5-(hydroxymethyl)cyclopentane-1,2,3-triol, STRICTOSIDINE-O-BETA-D-GLUCOSIDASE
著者Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J.
登録日2013-01-17
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
4RE0
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BU of 4re0 by Molmil
Crystal structure of VmoLac in P622 space group
分子名称: COBALT (II) ION, GLYCEROL, MYRISTIC ACID, ...
著者Hiblot, J, Bzdrenga, J, Champion, C, Gotthard, G, Gonzalez, D, Chabriere, E, Elias, M.
登録日2014-09-20
公開日2015-02-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia.
Sci Rep, 5, 2015
3JZS
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Human MDM2 liganded with a 12mer peptide inhibitor (pDIQ)
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, pDIQ peptide (12mer)
著者Schonbrunn, E, Phan, J.
登録日2009-09-24
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285, 2010
1AQC
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BU of 1aqc by Molmil
X11 PTB DOMAIN-10MER PEPTIDE COMPLEX
分子名称: PEPTIDE, X11
著者Lee, C.-H, Zhang, Z, Kuriyan, J.
登録日1997-07-28
公開日1997-12-24
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
8GU3
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Crystal structure of Caenorhabditis elegans METT-10 methyltransferase domain
分子名称: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
著者Ju, J, Tomita, K.
登録日2022-09-09
公開日2023-02-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structure of the Caenorhabditis elegans m6A methyltransferase METT10 that regulates SAM homeostasis.
Nucleic Acids Res., 51, 2023
8GPN
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BU of 8gpn by Molmil
Human menin in complex with H3K79Me2 nucleosome
分子名称: DNA (177-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Lin, J, Yu, D, Lam, W.H, Dang, S, Zhai, Y, Li, X.D.
登録日2022-08-26
公開日2023-02-15
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Menin "reads" H3K79me2 mark in a nucleosomal context.
Science, 379, 2023
3K72
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Structure of integrin alphaX beta2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-11
公開日2010-01-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
4QSE
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BU of 4qse by Molmil
Crystal structure of ATU4361 sugar transporter from Agrobacterium Fabrum c58, target efi-510558, with bound glycerol
分子名称: ABC-TYPE SUGAR TRANSPORTER, GLYCEROL
著者Patskovsky, Y, Toro, R, Bhosle, R, Al Obaidi, N, Chamala, S, Attonito, K.L, Scott Glenn, A, Chowdhury, S, Lafleur, J, Siedel, R.D, Hillerich, B, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-07-03
公開日2014-08-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Crystal structure of maltoside transporter ATU4361 from Agrobacterium Fabrum, target EFI-510558
To be Published
3ZQ5
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Structure of the Y263F mutant of the cyanobacterial phytochrome Cph1
分子名称: ACETATE ION, GLYCEROL, PHOSPHATE ION, ...
著者Mailliet, J, Psakis, G, Sineshchekov, V, Essen, L.-O, Hughes, J.
登録日2011-06-07
公開日2011-11-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Spectroscopy and a High-Resolution Crystal Structure of Tyr263 Mutants of Cyanobacterial Phytochrome Cph1.
J.Mol.Biol., 413, 2011
5FKS
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BU of 5fks by Molmil
Unraveling the first step of xyloglucan degradation by the soil saprophyte Cellvibrio japonicus through the functional and structural characterization of a potent GH74 endo-xyloglucanase
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, ENDO-1,4-BETA-GLUCANASE/XYLOGLUCANASE, ...
著者Attia, M, Stepper, J, Davies, G.J, Brumer, H.
登録日2015-10-19
公開日2015-11-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Functional and Structural Characterization of a Potent Gh74 Endo-Xyloglucanase from the Soil Saprophyte Cellvibrio Japonicus Unravels the First Step of Xyloglucan Degradation.
FEBS J., 283, 2016
5M17
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BU of 5m17 by Molmil
Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-1,2-dideoxymannose
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Glycosyl hydrolase family 71, ...
著者Petricevic, M, Sobala, L.F, Fernandes, P.Z, Raich, L, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J.
登録日2016-10-07
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-alpha-1,2-Mannanase.
J. Am. Chem. Soc., 139, 2017
1U8G
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BU of 1u8g by Molmil
Crystal structure of a HIV-1 Protease in complex with peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
分子名称: PROTEASE RETROPEPSIN, peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
著者Brynda, J, Rezacova, P, Fabry, M, Horejsi, M, Hradilek, M, Soucek, R, Stouracova, R, Konvalinka, J, Sedlacek, J.
登録日2004-08-06
公開日2004-11-02
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Inhibitor binding at the protein interface in crystals of a HIV-1 protease complex.
Acta Crystallogr.,Sect.D, 60, 2004
4QX3
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BU of 4qx3 by Molmil
Cry3A Toxin structure obtained by injecting Bacillus thuringiensis cells in an XFEL beam, collecting data by serial femtosecond crystallographic methods and processing data with the CrystFEL software suite
分子名称: Pesticidal crystal protein cry3Aa
著者Sawaya, M.R, Cascio, D, Gingery, M, Rodriguez, J, Goldschmidt, L, Colletier, J.-P, Messerschmidt, M, Boutet, S, Koglin, J.E, Williams, G.J, Brewster, A.S, Nass, K, Hattne, J, Botha, S, Doak, R.B, Shoeman, R.L, DePonte, D.P, Park, H.-W, Federici, B.A, Sauter, N.K, Schlichting, I, Eisenberg, D.
登録日2014-07-17
公開日2014-08-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Protein crystal structure obtained at 2.9 angstrom resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Proc.Natl.Acad.Sci.USA, 111, 2014
3K6S
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BU of 3k6s by Molmil
Structure of integrin alphaXbeta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-09
公開日2010-01-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
3ZXI
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BU of 3zxi by Molmil
Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with a tyrosyl-adenylate analog
分子名称: PHOSPHORIC ACID 2-AMINO-3-(4-HYDROXY-PHENYL)-PROPYL ESTER ADENOSIN-5'YL ESTER, TYROSYL-TRNA SYNTHETASE, MITOCHONDRIAL
著者Bonnefond, L, Frugier, M, Rudinger-Thirion, J, Balg, C, Chenevert, R, Lorber, B, Giege, R, Sauter, C.
登録日2011-08-11
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Exploiting Protein Engineering and Crystal Polymorphism for Successful X-Ray Structure Determination
Cryst.Growth Des., 11, 2011
5FOA
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Crystal Structure of Human Complement C3b in complex with DAF (CCP2-4)
分子名称: COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA CHAIN, DECAY ACCELERATING FACTOR, ...
著者Forneris, F, Wu, J, Xue, X, Gros, P.
登録日2015-11-18
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.188 Å)
主引用文献Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
5LSK
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BU of 5lsk by Molmil
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C COMPLEX
分子名称: Centromere protein C, Kinetochore-associated protein DSN1 homolog, Kinetochore-associated protein NSL1 homolog, ...
著者Vetter, I.R, Petrovic, A, Keller, J, Liu, Y.
登録日2016-09-02
公開日2016-11-16
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.502 Å)
主引用文献Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
Cell, 167, 2016
5LTC
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Crystal structure of doubly spin labelled VcSiaP R125
分子名称: C4-dicarboxylate-binding periplasmic protein
著者Peter, M, Glaenzer, J, Hagelueken, G.
登録日2016-09-06
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献PELDOR Spectroscopy Reveals Two Defined States of a Sialic Acid TRAP Transporter SBP in Solution.
Biophys. J., 112, 2017
5LUX
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BU of 5lux by Molmil
Homeobox transcription factor CDX1 bound to methylated DNA
分子名称: DNA (5'-D(P*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*CP*CP*TP*C)-3'), ...
著者Morgunova, E, Popov, A, Taipale, J.
登録日2016-09-12
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
6JCA
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Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in I222 space group
分子名称: CHLORIDE ION, CrmG, GLYCEROL, ...
著者Xu, J, Liu, J.
登録日2019-01-28
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition.
Commun Biol, 3, 2020

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