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PDB: 17801 件

6TI3
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Apo-SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with D-Threonine
分子名称: D-THREONINE, GLYCEROL, SODIUM ION, ...
著者Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I.
登録日2019-11-21
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus
To Be Published
6WPL
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BU of 6wpl by Molmil
Structure of Cytochrome P450tcu
分子名称: 5-EXO-HYDROXYCAMPHOR, Cytochrome P-450cam, subunit of camphor 5-monooxygenase system, ...
著者Murarka, V.C, Batabyal, D, Amaya, J.A, Sevrioukova, I.F, Poulos, T.L.
登録日2020-04-27
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Unexpected Differences between Two Closely Related Bacterial P450 Camphor Monooxygenases.
Biochemistry, 59, 2020
6Q20
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Crystal structure of human 1E01 Fab in complex with influenza virus neuraminidase from A/Japan/305/1957 (H2N2)
分子名称: 1E01 Fab IgG1 heavy chain, 1E01 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019
5CEX
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Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
分子名称: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
著者Garces, F, Wilson, I.A.
登録日2015-07-07
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
6X1W
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BU of 6x1w by Molmil
Structure of pHis Fab (SC56-2) in complex with pHis mimetic peptide
分子名称: ACLYana-3-pTza peptide, SC56-2 Heavy chain, SC56-2 Light chain
著者Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T.
登録日2020-05-19
公開日2021-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
2CN2
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BU of 2cn2 by Molmil
Crystal Structures of Clostridium thermocellum Xyloglucanase
分子名称: BETA-1,4-XYLOGLUCAN HYDROLASE, CADMIUM ION
著者Martinez-Fleites, C, Taylor, E.J, Guerreiro, C.I, Prates, J.A.M, Ferreira, L.M.A, Fontes, C.M.G.A, Baumann, M.J, Brumer, H, Davies, G.J.
登録日2006-05-17
公開日2006-05-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Clostridium Thermocellum Xyloglucanase, Xgh74A, Reveal the Structural Basis for Xyloglucan Recognition and Degradation.
J.Biol.Chem., 281, 2006
6TNQ
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BU of 6tnq by Molmil
Crystal structure of the human Arc N-lobe bound to repeat 4 from GKAP
分子名称: ACETYL GROUP, Activity-regulated cytoskeleton-associated protein, Chains: B,D,F
著者Hallin, E.I, Bramham, C.R, Kursula, P.
登録日2019-12-10
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural properties and peptide ligand binding of the capsid homology domains of human Arc.
Biochem Biophys Rep, 26, 2021
6WLM
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F. nucleatum glycine riboswitch with glycine models, 7.4 Angstrom resolution
分子名称: RNA (171-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6PW4
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Cryo-EM Structure of Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas reinhardtii in Detergent
分子名称: (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
著者McGoldrick, L.L, Singh, A.K, Sobolevsky, A.I.
登録日2019-07-22
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii.
Nat Commun, 10, 2019
6PXE
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BU of 6pxe by Molmil
Crystal structure of the complex between periplasmic domains of antiholin RI and holin T from T4 phage, in P21
分子名称: Antiholin, Holin
著者Krieger, I.V, Sacchettini, J.C.
登録日2019-07-25
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition.
J.Mol.Biol., 432, 2020
1TJC
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BU of 1tjc by Molmil
Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase
分子名称: Prolyl 4-hydroxylase alpha-1 subunit
著者Pekkala, M, Hieta, R, Bergmann, U, Kivirikko, K.I, Wierenga, R.K, Myllyharju, J.
登録日2004-06-04
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Peptide-Substrate-binding Domain of Collagen Prolyl 4-Hydroxylases Is a Tetratricopeptide Repeat Domain with Functional Aromatic Residues.
J.Biol.Chem., 279, 2004
4IV1
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BU of 4iv1 by Molmil
Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Porta, C, Kotecha, A, Burman, A, Jackson, T, Ren, J, Loureiro, S, Jones, I.M, Fry, E.E, Stuart, D.I, Charleston, B.
登録日2013-01-22
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
5KHH
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BU of 5khh by Molmil
HCN2 CNBD in complex with inosine-3', 5'-cyclic monophosphate (cIMP)
分子名称: Inosine-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
登録日2016-06-14
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
6Q9F
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BU of 6q9f by Molmil
Aspartyl/Asparaginyl beta-hydroxylase (AspH) H679A in complex with Mn, NOG and Factor X peptide fragment (39mer-4Ser)
分子名称: Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, GLYCEROL, ...
著者Chowdhury, R, Pfeffer, I, Schofield, C.J.
登録日2018-12-18
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Aspartyl/Asparaginyl beta-hydroxylase (AspH) H679A in complex with Mn, NOG and Factor X peptide fragment (39mer-4Ser)
To Be Published
6Q9I
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BU of 6q9i by Molmil
Aspartyl/Asparaginyl beta-hydroxylase (AspH) H679A in complex with Factor X peptide fragment (39mer-4Ser)
分子名称: Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, FORMIC ACID, ...
著者Chowdhury, R, Pfeffer, I, Schofield, C.J.
登録日2018-12-18
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献AspH-H679A.Factor X Complex
To Be Published
4AFL
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BU of 4afl by Molmil
The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.
分子名称: INHIBITOR OF GROWTH PROTEIN 4
著者Culurgioni, S, Munoz, I.G, Moreno, A, Palacios, A, Villate, M, Palmero, I, Montoya, G, Blanco, F.J.
登録日2012-01-19
公開日2012-02-22
最終更新日2012-07-11
実験手法X-RAY DIFFRACTION (2.275 Å)
主引用文献Crystal Structure of Inhibitor of Growth 4 (Ing4) Dimerization Domain Reveals Functional Organization of Ing Family of Chromatin-Binding Proteins.
J.Biol.Chem., 287, 2012
6WLR
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SAM-IV riboswitch with SAM models, 4.8 Angstrom resolution
分子名称: RNA (119-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6TTZ
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BU of 6ttz by Molmil
Structure of the ClpP:ADEP4-complex from Staphylococcus aureus (open state)
分子名称: ATP-dependent Clp protease proteolytic subunit, N-[(2S)-3-(3,5-difluorophenyl)-1-[[(3S,9S,13S,15R,19S,22S)-15,19-dimethyl-2,8,12,18,21-pentaoxo-11-oxa-1,7,17,20-tetrazatetracyclo[20.4.0.03,7.013,17]hexacosan-9-yl]amino]-1-oxopropan-2-yl]heptanamide
著者Malik, I.T, Pereira, R, Vielberg, M.-T, Mayer, C, Straetener, J, Thomy, D, Famulla, K, Castro, H.C, Sass, P, Groll, M, Broetz-Oesterheldt, H.
登録日2019-12-30
公開日2020-03-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes.
Chembiochem, 21, 2020
6WOR
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BU of 6wor by Molmil
Structure of the broadly neutralizing antibody HC1AM
分子名称: Fab HC1AM heavy chain, Fab HC1AM light chain
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-04-25
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WLS
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Tetrahymena ribozyme models, 6.8 Angstrom resolution
分子名称: RNA (388-MER)
著者Kappel, K, Zhang, K, Su, Z, Watkins, A.M, Kladwang, W, Li, S, Pintilie, G, Topkar, V.V, Rangan, R, Zheludev, I.N, Yesselman, J.D, Chiu, W, Das, R.
登録日2020-04-20
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Nat.Methods, 17, 2020
6WP7
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Avenolide Binding Autoregulator AvaR1
分子名称: AvaR1
著者Kapoor, I, Olivares, P.J, Nair, S.K.
登録日2020-04-26
公開日2020-06-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones.
Elife, 9, 2020
6WPD
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NMR Structure of HSP1-NH2 antimicrobial peptide in presence of DPC-d38 micelles
分子名称: HSP1-NH2
著者Verly, R.M, Gomes, I.P.
登録日2020-04-27
公開日2020-09-02
最終更新日2020-09-16
実験手法SOLUTION NMR
主引用文献Membrane interactions of the anuran antimicrobial peptide HSP1-NH2: Different aspects of the association to anionic and zwitterionic biomimetic systems.
Biochim Biophys Acta Biomembr, 1863, 2020
6WPB
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NMR Structure of HSP1-NH2 antimicrobial peptide in presence of SDS-d25 micelles
分子名称: HSP1-NH2
著者Verly, R.M, Gomes, I.P.
登録日2020-04-27
公開日2020-09-02
最終更新日2020-09-16
実験手法SOLUTION NMR
主引用文献Membrane interactions of the anuran antimicrobial peptide HSP1-NH2: Different aspects of the association to anionic and zwitterionic biomimetic systems.
Biochim Biophys Acta Biomembr, 1863, 2020
1TIQ
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BU of 1tiq by Molmil
Crystal Structure of an Acetyltransferase (PaiA) in complex with CoA and DTT from Bacillus subtilis, Northeast Structural Genomics Target SR64.
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, COENZYME A, Protease synthase and sporulation negative regulatory protein PAI 1, ...
著者Forouhar, F, Lee, I, Shen, J, Vorobiev, S.M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2004-06-02
公開日2004-07-13
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase.
J.Biol.Chem., 280, 2005
7CQE
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Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with AZD-7762
分子名称: 5-(3-fluorophenyl)-N-[(3S)-3-piperidyl]-3-ureido-thiophene-2-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
著者Park, T.H, Lee, B.I.
登録日2020-08-10
公開日2020-11-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Crystal Structure of the Kinase Domain of MerTK in Complex with AZD7762 Provides Clues for Structure-Based Drug Development.
Int J Mol Sci, 21, 2020

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件を2024-08-07に公開中

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