6X1W

Structure of pHis Fab (SC56-2) in complex with pHis mimetic peptide

Summary for 6X1W

Entry DOI	10.2210/pdb6x1w/pdb
Descriptor	SC56-2 Heavy chain, SC56-2 Light chain, ACLYana-3-pTza peptide, ... (4 entities in total)
Functional Keywords	anti-phosphohistidine antibody, post-translational modification, immune system
Biological source	Oryctolagus cuniculus More
Total number of polymer chains	3
Total formula weight	47864.79
Authors	Kalagiri, R.,Stanfield, R.,Wilson, I.A.,Hunter, T. (deposition date: 2020-05-19, release date: 2021-02-03, Last modification date: 2023-11-15)
Primary citation	Kalagiri, R.,Stanfield, R.L.,Meisenhelder, J.,La Clair, J.J.,Fuhs, S.R.,Wilson, I.A.,Hunter, T. Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33547238 DOI: 10.1073/pnas.2010644118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation