Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 46 件
2IEP
DownloadVisualize
BU of 2iep by Molmil
Crystal structure of immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK
分子名称: Muscle-specific kinase receptor, SULFATE ION
著者Stiegler, A.L, Burden, S.J, Hubbard, S.R.
登録日2006-09-19
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献Crystal Structure of the Agrin-responsive Immunoglobulin-like Domains 1 and 2 of the Receptor Tyrosine Kinase MuSK
J.Mol.Biol., 364, 2006
2HDV
DownloadVisualize
BU of 2hdv by Molmil
Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B
分子名称: SH2-B PH domain containing signaling mediator 1 gamma isoform
著者Hu, J, Hubbard, S.R.
登録日2006-06-20
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2HDX
DownloadVisualize
BU of 2hdx by Molmil
Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
分子名称: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform
著者Hu, J, Hubbard, S.R.
登録日2006-06-21
公開日2006-08-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2HMH
DownloadVisualize
BU of 2hmh by Molmil
Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide.
分子名称: Interleukin-6 receptor beta chain, Suppressor of cytokine signaling 3
著者Bergamin, E, Wu, J, Hubbard, S.R.
登録日2006-07-11
公開日2006-08-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3.
Structure, 14, 2006
1GAG
DownloadVisualize
BU of 1gag by Molmil
CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH A BISUBSTRATE INHIBITOR
分子名称: BISUBSTRATE PEPTIDE INHIBITOR, INSULIN RECEPTOR, TYROSINE KINASE DOMAIN, ...
著者Parang, K, Till, J.H, Ablooglu, A.J, Kohanski, R.A, Hubbard, S.R, Cole, P.A.
登録日2000-11-29
公開日2001-01-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism-based design of a protein kinase inhibitor.
Nat.Struct.Biol., 8, 2001
1FGI
DownloadVisualize
BU of 1fgi by Molmil
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 IN COMPLEX WITH SU5402 INHIBITOR
分子名称: 3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE, FGF RECEPTOR 1
著者Mohammadi, M, Schlessinger, J, Hubbard, S.R.
登録日1997-03-22
公開日1998-04-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.
Science, 276, 1997
4FVP
DownloadVisualize
BU of 4fvp by Molmil
Crystal structure of the Jak2 pseudokinase domain (apo form)
分子名称: GLYCEROL, Tyrosine-protein kinase JAK2
著者Bandaranayake, R.M, Hubbard, S.R.
登録日2012-06-29
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012
4FVR
DownloadVisualize
BU of 4fvr by Molmil
Crystal structure of the Jak2 pseudokinase domain mutant V617F (Mg-ATP-bound form)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tyrosine-protein kinase JAK2
著者Bandaranayake, R.M, Hubbard, S.R.
登録日2012-06-29
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012
4FVQ
DownloadVisualize
BU of 4fvq by Molmil
Crystal structure of the Jak2 pseudokinase domain (Mg-ATP-bound form)
分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Bandaranayake, R.M, Hubbard, S.R.
登録日2012-06-29
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012
1EV2
DownloadVisualize
BU of 1ev2 by Molmil
CRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
分子名称: PROTEIN (FIBROBLAST GROWTH FACTOR 2), PROTEIN (FIBROBLAST GROWTH FACTOR RECEPTOR 2), SULFATE ION
著者Plotnikov, A.N, Hubbard, S.R, Schlessinger, J, Mohammadi, M.
登録日2000-04-19
公開日2000-05-31
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Cell(Cambridge,Mass.), 101, 2000
1EVT
DownloadVisualize
BU of 1evt by Molmil
CRYSTAL STRUCTURE OF FGF1 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 1 (FGFR1)
分子名称: PROTEIN (FIBROBLAST GROWTH FACTOR 1), PROTEIN (FIBROBLAST GROWTH FACTOR RECEPTOR 1), SULFATE ION
著者Plotnikov, A.N, Hubbard, S.R, Schlessinger, J, Mohammadi, M.
登録日2000-04-20
公開日2000-05-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Cell(Cambridge,Mass.), 101, 2000
1P14
DownloadVisualize
BU of 1p14 by Molmil
Crystal structure of a catalytic-loop mutant of the insulin receptor tyrosine kinase
分子名称: insulin receptor
著者Li, S, Covino, N.D, Stein, E.G, Till, J.H, Hubbard, S.R.
登録日2003-04-11
公開日2003-07-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor
J.Biol.Chem., 278, 2003
1NRV
DownloadVisualize
BU of 1nrv by Molmil
Crystal structure of the SH2 domain of Grb10
分子名称: Growth factor receptor-bound protein 10
著者Stein, E.G, Hubbard, S.R.
登録日2003-01-25
公開日2003-04-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity.
J.Biol.Chem., 278, 2003
1FGK
DownloadVisualize
BU of 1fgk by Molmil
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1
分子名称: FGF RECEPTOR 1
著者Mohammadi, M, Schlessinger, J, Hubbard, S.R.
登録日1997-02-08
公開日1997-07-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism.
Cell(Cambridge,Mass.), 86, 1996
1RQQ
DownloadVisualize
BU of 1rqq by Molmil
Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS
分子名称: BISUBSTRATE INHIBITOR, Insulin receptor, MANGANESE (II) ION, ...
著者Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R.
登録日2003-12-06
公開日2003-12-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
1I44
DownloadVisualize
BU of 1i44 by Molmil
CRYSTALLOGRAPHIC STUDIES OF AN ACTIVATION LOOP MUTANT OF THE INSULIN RECEPTOR TYROSINE KINASE
分子名称: INSULIN RECEPTOR, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Till, J.H, Ablooglu, A.J, Frankel, M, Kohanski, R.A, Hubbard, S.R.
登録日2001-02-19
公開日2001-03-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.
J.Biol.Chem., 276, 2001
1RPY
DownloadVisualize
BU of 1rpy by Molmil
CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS
分子名称: SULFATE ION, adaptor protein APS
著者Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R.
登録日2003-12-03
公開日2003-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
3BCH
DownloadVisualize
BU of 3bch by Molmil
Crystal Structure of the Human Laminin Receptor Precursor
分子名称: 40S ribosomal protein SA
著者Jamieson, K.V, Wu, J, Hubbard, S.R, Meruelo, D.
登録日2007-11-12
公開日2007-12-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the human laminin receptor precursor.
J.Biol.Chem., 283, 2008
3BU5
DownloadVisualize
BU of 3bu5 by Molmil
Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Insulin receptor substrate 2, MAGNESIUM ION, ...
著者Wu, J, Hubbard, S.R.
登録日2007-12-31
公開日2008-02-19
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3BU3
DownloadVisualize
BU of 3bu3 by Molmil
Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide
分子名称: Insulin receptor substrate 2, insulin receptor subunit beta
著者Wu, J, Hubbard, S.R.
登録日2007-12-31
公開日2008-02-19
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
3BU6
DownloadVisualize
BU of 3bu6 by Molmil
Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB phosphopeptide
分子名称: Insulin receptor substrate 2, insulin receptor subunit beta
著者Wu, J, Hubbard, S.R.
登録日2007-12-31
公開日2008-02-19
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.
Nat.Struct.Mol.Biol., 15, 2008
<12

 

226262

件を2024-10-16に公開中

PDB statisticsPDBj update infoContact PDBjnumon