Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1FGI

CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 IN COMPLEX WITH SU5402 INHIBITOR

Summary for 1FGI
Entry DOI10.2210/pdb1fgi/pdb
DescriptorFGF RECEPTOR 1, 3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE (3 entities in total)
Functional Keywordsprotein kinase, transferase, tyrosine-protein kinase, atp-binding, phosphorylation, inhibitor
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein: P11362
Total number of polymer chains2
Total formula weight71209.87
Authors
Mohammadi, M.,Schlessinger, J.,Hubbard, S.R. (deposition date: 1997-03-22, release date: 1998-04-08, Last modification date: 2024-02-07)
Primary citationMohammadi, M.,McMahon, G.,Sun, L.,Tang, C.,Hirth, P.,Yeh, B.K.,Hubbard, S.R.,Schlessinger, J.
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.
Science, 276:955-960, 1997
Cited by
PubMed: 9139660
DOI: 10.1126/science.276.5314.955
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon