1RPY

CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS

Summary for 1RPY

• Entry DOI: 10.2210/pdb1rpy/pdb
• Descriptor: adaptor protein APS, SULFATE ION (3 entities in total)
• Functional Keywords: adapter protein, sh2 domain, signaling protein
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Cytoplasm: Q9Z200
• Total number of polymer chains: 2
• Total formula weight: 26069.27

Authors

Hu, J.,Liu, J.,Ghirlando, R.,Saltiel, A.R.,Hubbard, S.R. (deposition date: 2003-12-03, release date: 2003-12-23, Last modification date: 2011-07-13)

• Primary citation: Hu, J.,Liu, J.,Ghirlando, R.,Saltiel, A.R.,Hubbard, S.R.; Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.; Mol.Cell, 12:1379-1389, 2003; PubMed: 14690593; DOI: 10.1016/S1097-2765(03)00487-8

Experimental method

X-RAY DIFFRACTION (2.3 Å)