8JJN
 
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8K5U
 | | Se-glycosyltransferase RsSenB | | Descriptor: | Se glycosyltransferase | | Authors: | Huang, W, Long, F. | | Deposit date: | 2023-07-24 | | Release date: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of RsSenB at 2.15 Angstroms resolution
To Be Published
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8FZR
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4HKA
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2LJV
 | | Solution structure of Rhodostomin G50L mutant | | Descriptor: | Disintegrin rhodostomin | | Authors: | Chuang, W, Shiu, J, Chen, C, Chen, Y, Chang, Y, Huang, C. | | Deposit date: | 2011-09-29 | | Release date: | 2012-10-03 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy
To be Published
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7DUC
 | | Crystal Structure of cyto WalK | | Descriptor: | Sensor protein kinase WalK, ZINC ION | | Authors: | Huang, W. | | Deposit date: | 2021-01-08 | | Release date: | 2022-01-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Crystal Structure of cyto WalK
To Be Published
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7DUD
 | | Crystal Structure of erWalK | | Descriptor: | Sensor protein kinase WalK | | Authors: | Huang, W. | | Deposit date: | 2021-01-08 | | Release date: | 2022-01-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal Structure of erWalK
To Be Published
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2JTC
 | | 3D structure and backbone dynamics of SPE B | | Descriptor: | Streptopain | | Authors: | Chuang, W, Wang, C, Houng, H, Chen, C, Wang, P. | | Deposit date: | 2007-07-26 | | Release date: | 2008-08-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure and backbone dynamics of streptopain: insight into diverse substrate specificity.
J.Biol.Chem., 284, 2009
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2M75
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2M7H
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2M7F
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2KIU
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6E53
 | | Structure of TERT in complex with a novel telomerase inhibitor | | Descriptor: | MAGNESIUM ION, RNA/DNA hairpin, Telomerase reverse transcriptase, ... | | Authors: | Hernandez-Sanchez, W, Huang, W, Plucinsky, B, Garcia-Vazquez, N, Berdis, A.J, Skordalakes, E, Taylor, D.J. | | Deposit date: | 2018-07-19 | | Release date: | 2019-03-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol., 17, 2019
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1EAP
 | | CRYSTAL STRUCTURE OF A CATALYTIC ANTIBODY WITH A SERINE PROTEASE ACTIVE SITE | | Descriptor: | IGG2B-KAPPA 17E8 FAB (HEAVY CHAIN), IGG2B-KAPPA 17E8 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE | | Authors: | Zhou, G.W, Guo, J, Huang, W, Scanlan, T.S, Fletterick, R.J. | | Deposit date: | 1994-08-10 | | Release date: | 1994-12-20 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of a catalytic antibody with a serine protease active site.
Science, 265, 1994
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1ONR
 | | STRUCTURE OF TRANSALDOLASE B | | Descriptor: | TRANSALDOLASE B | | Authors: | Jia, J, Huang, W, Lindqvist, Y, Schneider, G. | | Deposit date: | 1996-08-13 | | Release date: | 1997-03-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family.
Structure, 4, 1996
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8IR4
 | | Crystal structure of the SLF1 BRCT domain in complex with a Rad18 peptide containing pS442 | | Descriptor: | CHLORIDE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | | Authors: | Xiang, S, Huang, W, Qiu, F. | | Deposit date: | 2023-03-17 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structural insights into Rad18 targeting by the SLF1 BRCT domains.
J.Biol.Chem., 299, 2023
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8IR2
 | | Crystal structure of the SLF1 BRCT domain in complex with a Rad18 peptide containing pS442 and pS444 | | Descriptor: | CHLORIDE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | | Authors: | Xiang, S, Huang, W, Qiu, F. | | Deposit date: | 2023-03-17 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural insights into Rad18 targeting by the SLF1 BRCT domains.
J.Biol.Chem., 299, 2023
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6UP7
 | | neurotensin receptor and arrestin2 complex | | Descriptor: | ARG-ARG-PRO-TYR-ILE-LEU, Beta-arrestin-1, Neurotensin receptor type 1, ... | | Authors: | Qu, Q.H, Huang, W, Masureel, M, Janetzko, J, Kobilka, B.K, Skiniotis, G. | | Deposit date: | 2019-10-16 | | Release date: | 2020-02-26 | | Last modified: | 2020-06-17 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structure of the neurotensin receptor 1 in complex with beta-arrestin 1.
Nature, 579, 2020
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1XDO
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1XDP
 | | Crystal Structure of the E.coli Polyphosphate Kinase in complex with AMPPNP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyphosphate kinase | | Authors: | Zhu, Y, Huang, W, Lee, S.S, Xu, W. | | Deposit date: | 2004-09-07 | | Release date: | 2005-06-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a polyphosphate kinase and its implications for polyphosphate synthesis
Embo Rep., 6, 2005
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8YRF
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1AFR
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1D2L
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3EZR
 | | CDK-2 with indazole inhibitor 17 bound at its active site | | Descriptor: | 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 | | Authors: | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | | Deposit date: | 2008-10-23 | | Release date: | 2009-02-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor
Bioorg.Med.Chem.Lett., 19, 2009
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3F5X
 | | CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site | | Descriptor: | 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2, Cyclin-A2, ... | | Authors: | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | | Deposit date: | 2008-11-04 | | Release date: | 2009-02-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor.
Bioorg.Med.Chem.Lett., 19, 2009
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