1D2L

NMR SOLUTION STRUCTURE OF COMPLEMENT-LIKE REPEAT CR3 FROM THE LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN (LRP). EVIDENCE FOR SPECIFIC BINDING TO THE RECEPTOR BINDING DOMAIN OF HUMAN ALPHA-2 MACROGLOBULIN

Summary for 1D2L

Related1CR8
DescriptorLIPOPROTEIN RECEPTOR RELATED PROTEIN, CALCIUM ION (2 entities in total)
Functional Keywordsligand binding, calcium binding, complement-like repeat, receptor, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationLow-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; Extracellular side. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm Q07954
Total number of polymer chains1
Total molecular weight4992.43
Authors
Dolmer, K.,Huang, W.,Gettins, P.G.W. (deposition date: 1999-09-24, release date: 2000-01-14, Last modification date: 2011-07-13)
Primary citation
Dolmer, K.,Huang, W.,Gettins, P.G.
NMR solution structure of complement-like repeat CR3 from the low density lipoprotein receptor-related protein. Evidence for specific binding to the receptor binding domain of human alpha(2)-macroglobulin.
J.Biol.Chem., 275:3264-3269, 2000
PubMed: 10652313 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.275.5.3264
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers1 9.7% 24.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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170172
PDB entries from 2020-10-21