8IQ4
| Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | Deposit date: | 2023-03-15 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity. Nat Commun, 14, 2023
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8JMM
| Structure of XBB spike protein (S) dimer-trimer in complex with bispecific antibody G7-Fc at 3.75 Angstroms resolution. | Descriptor: | 7F3 Fv, GW01 Fv, Spike glycoprotein | Authors: | Hao, A, Mao, Q, Chen, Z, Huang, J, Sun, L. | Deposit date: | 2023-06-05 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure of XBB spike protein (S) dimer-trimer in complex with bispecific antibody G7-Fc at 3.75 Angstroms resolution. To Be Published
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3TYH
| Crystal structure of oxo-cupper clusters binding to ferric binding protein from Neisseria gonorrhoeae | Descriptor: | COPPER (II) ION, FbpA protein | Authors: | Chen, W.J, Wang, H.F, Zhou, C.J, Ye, D.R, Huang, J, Tan, X.S, Zhong, W.Q. | Deposit date: | 2011-09-26 | Release date: | 2012-09-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of oxo-cupper clusters binding to ferric binding protein from Neisseria gonorrhoeae To be Published
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4E9A
| Structure of Peptide Deformylase form Helicobacter Pylori in complex with inhibitor | Descriptor: | 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COBALT (II) ION, ... | Authors: | Cui, K, Zhu, L, Lu, W, Huang, J. | Deposit date: | 2012-03-20 | Release date: | 2013-04-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.662 Å) | Cite: | Identification of Novel Peptide Deformylase Inhibitors from Natural Products To be Published
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3J1U
| Low affinity dynein microtubule binding domain - tubulin complex | Descriptor: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | Authors: | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | Deposit date: | 2012-06-25 | Release date: | 2012-09-26 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Structural basis for microtubule binding and release by dynein. Science, 337, 2012
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3J1T
| High affinity dynein microtubule binding domain - tubulin complex | Descriptor: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | Authors: | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | Deposit date: | 2012-06-25 | Release date: | 2012-09-26 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Structural basis for microtubule binding and release by dynein. Science, 337, 2012
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7CX0
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor carbidopa | Descriptor: | CARBIDOPA, Decarboxylase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | Deposit date: | 2020-09-01 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor carbidopa to be published
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7CX1
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor methyl-tyrosine | Descriptor: | 4-[(2R)-2-(methylamino)propyl]phenol, Decarboxylase | Authors: | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | Deposit date: | 2020-09-01 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor methyl-tyrosine to be published
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7CWZ
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis K392A mutant in complex with the cofactor PLP and L-dopa | Descriptor: | Decarboxylase, L-DOPAMINE, MAGNESIUM ION, ... | Authors: | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | Deposit date: | 2020-09-01 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis K392A mutant in complex with the cofactor PLP and L-dopa to be published
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4E9B
| Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACTINONIN, COBALT (II) ION, ... | Authors: | Cui, K, Zhu, L, Lu, W, Huang, J. | Deposit date: | 2012-03-20 | Release date: | 2013-04-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Identification of Novel Peptide Deformylase Inhibitors from Natural Products To be Published
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5H2Z
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6J99
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6YPZ
| Promiscuous Reductase LugOII Catalyzes Keto-reduction at C1 during Lugdunomycin Biosynthesis | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Monooxygenase, ... | Authors: | Xiao, X, Elsayed, S.S, Wu, C, van der Heul, H, Prota, A, Huang, J, Guo, R, Abrahams, J.P, van Wezel, G.P. | Deposit date: | 2020-04-16 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway. Acs Chem.Biol., 15, 2020
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6YQ6
| Promiscuous Reductase LugOII Catalyzes Keto-reduction at C1 during Lugdunomycin Biosynthesis | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Monooxygenase, ... | Authors: | Xiao, X, Elsayed, S.S, Wu, C, van der Heul, H, Prota, A, Huang, J, Guo, R, Abrahams, J.P, van Wezel, G.P. | Deposit date: | 2020-04-16 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway. Acs Chem.Biol., 15, 2020
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6YQ3
| Promiscuous Reductase LugOII Catalyzes Keto-reduction at C1 during Lugdunomycin Biosynthesis | Descriptor: | (3~{R})-8-methoxy-3-methyl-3,6-bis(oxidanyl)-2,4-dihydrobenzo[a]anthracene-1,7,12-trione, 1,2-ETHANEDIOL, Monooxygenase, ... | Authors: | Xiao, X, Elsayed, S.S, Wu, C, van der Heul, H, Prota, A, Huang, J, Guo, R, Abrahams, J.P, van Wezel, G.P. | Deposit date: | 2020-04-16 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway. Acs Chem.Biol., 15, 2020
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4IG4
| Crystal structure of single mutant thermostable NPPase (N86S) from Geobacillus stearothermophilus | Descriptor: | Thermostable NPPase | Authors: | Guo, Z, Wang, F, Huang, J, Qiu, R, Yang, Z, Wang, Y, Gong, W, Ji, C. | Deposit date: | 2012-12-16 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Crystal structure of thermostable NPPase from Geobacillus stearothermophilus To be Published
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6YQ0
| Promiscuous Reductase LugOII Catalyzes Keto-reduction at C1 during Lugdunomycin Biosynthesis | Descriptor: | (3~{R})-8-methoxy-3-methyl-3-oxidanyl-2,4-dihydrobenzo[a]anthracene-1,7,12-trione, 1,2-ETHANEDIOL, Monooxygenase, ... | Authors: | Xiao, X, Elsayed, S.S, Wu, C, van der Heul, H, Prota, A, Huang, J, Guo, R, Abrahams, J.P, van Wezel, G.P. | Deposit date: | 2020-04-16 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway. Acs Chem.Biol., 15, 2020
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6JIC
| Identification and Characterization of a carboxypeptidase inhibitor from Lycium barbarum | Descriptor: | WCI | Authors: | Tan, W.L, Wong, K.H, Huang, J.Y, Tay, S.V, Wang, S.J. | Deposit date: | 2019-02-20 | Release date: | 2020-02-26 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Identification and characterization of a wolfberry carboxypeptidase inhibitor from Lycium barbarum. Food Chem, 351, 2021
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4IXL
| Crystal structure of endo-beta-1,4-xylanase from the alkaliphilic Bacillus sp. SN5 | Descriptor: | SULFATE ION, xylanase | Authors: | Bai, W.Q, Xue, Y.F, Huang, J.X, Zhou, C, Guo, R.T, Ma, Y.H. | Deposit date: | 2013-01-26 | Release date: | 2014-02-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structure Analysis of Alkaline xylanase from Alkaliphilic Bacillus sp. SN5 Implications for pH-dependent enzyme activity To be Published
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4IFT
| Crystal structure of double mutant thermostable NPPase from Geobacillus stearothermophilus | Descriptor: | Thermostable NPPase | Authors: | Guo, Z, Huang, J, Wang, F, Qiu, R, Wang, Y, Ji, C. | Deposit date: | 2012-12-15 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.995 Å) | Cite: | Crystal structure of thermostable NPPase from Geobacillus stearothermophilus To be Published
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3U58
| Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 AB | Descriptor: | DNA (5'-D(*GP*GP*GP*T)-3'), Tetrahymena Teb1 AB | Authors: | Zeng, Z, Huang, J, Yang, Y, Lei, M. | Deposit date: | 2011-10-11 | Release date: | 2011-12-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.613 Å) | Cite: | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA. Proc.Natl.Acad.Sci.USA, 108, 2011
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4KN8
| Crystal structure of Bs-TpNPPase | Descriptor: | Thermostable NPPase | Authors: | Guo, Z, Wang, F, Huang, J, Gong, W, Ji, C. | Deposit date: | 2013-05-09 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase) PROTEIN PEPT.LETT., 21, 2014
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5XZ4
| The X-tay structure of Bumblebee PGRP-SA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bumblebee peptidoglycan recognition protein SA, SULFATE ION | Authors: | Liu, Y.J, Huang, J.X, Zhao, X.M, An, J.D. | Deposit date: | 2017-07-11 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Structural Insights into the Preferential Binding of PGRP-SAs from Bumblebees and Honeybees to Dap-Type Peptidoglycans Rather than Lys-Type Peptidoglycans. J Immunol., 202, 2019
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7CWX
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis | Descriptor: | DI(HYDROXYETHYL)ETHER, Decarboxylase, GLYCEROL | Authors: | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | Deposit date: | 2020-09-01 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis to be published
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7CWY
| Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP | Descriptor: | Decarboxylase | Authors: | Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R. | Deposit date: | 2020-09-01 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP to be published
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