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PDB: 553 件
7RJF
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BU of 7rjf by Molmil
MOPD-1 mutant-L47W
分子名称: MALONATE ION, ZINC ION, [L47W]MOPD-1
著者Huawu, Y, Conan, K.W, Gordon, J.K, Brett, M.C, Yen-Hua, H, David, J.C.
登録日2021-07-20
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy.
J.Am.Chem.Soc., 143, 2021
5F54
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BU of 5f54 by Molmil
Structure of RecJ complexed with dTMP
分子名称: MANGANESE (II) ION, Single-stranded-DNA-specific exonuclease, THYMIDINE-5'-PHOSPHATE
著者Hua, Y, Zhao, Y, Cheng, K.
登録日2015-12-04
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
5F55
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BU of 5f55 by Molmil
Structure of RecJ complexed with DNA
分子名称: DNA (5'-D(*GP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*C)-3'), MANGANESE (II) ION, SULFATE ION, ...
著者Hua, Y, Zhao, Y, Cheng, K.
登録日2015-12-04
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
1CQU
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BU of 1cqu by Molmil
SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF RIBOSOMAL PROTEIN L9
分子名称: 50S RIBOSOMAL PROTEIN L9
著者Hua, Y, Kuhlman, B, Hoffman, D, Raleigh, D.P.
登録日1999-08-11
公開日2002-04-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Effects of varying the local propensity to form secondary structure on the stability and folding kinetics of a rapid folding mixed alpha/beta protein: characterization of a truncation mutant of the N-terminal domain of the ribosomal protein L9.
J.Mol.Biol., 289, 1999
7JVQ
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BU of 7jvq by Molmil
Cryo-EM structure of apomorphine-bound dopamine receptor 1 in complex with Gs protein
分子名称: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
登録日2020-08-22
公開日2021-02-24
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7JVP
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BU of 7jvp by Molmil
Cryo-EM structure of SKF-83959-bound dopamine receptor 1 in complex with Gs protein
分子名称: (1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
登録日2020-08-22
公開日2021-02-24
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7JV5
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BU of 7jv5 by Molmil
Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein
分子名称: (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
登録日2020-08-20
公開日2021-02-24
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7JVR
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BU of 7jvr by Molmil
Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein
分子名称: Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
登録日2020-08-22
公開日2021-02-24
最終更新日2021-03-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7LJC
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BU of 7ljc by Molmil
Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
分子名称: (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ...
著者Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
登録日2021-01-28
公開日2021-03-03
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
7LJD
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BU of 7ljd by Molmil
Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein
分子名称: 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ...
著者Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E.
登録日2021-01-28
公開日2021-03-03
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
5IN1
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BU of 5in1 by Molmil
Crystal Structure of the MRG701 chromodomain
分子名称: 1,2-ETHANEDIOL, MRG701, SULFATE ION
著者Huang, Y, Liu, Y.
登録日2016-03-07
公開日2017-03-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural studies on MRG701 chromodomain reveal a novel dimerization interface of MRG proteins in green plants
Protein Cell, 7, 2016
2GF7
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BU of 2gf7 by Molmil
Double tudor domain structure
分子名称: Jumonji domain-containing protein 2A, SULFATE ION
著者Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M.
登録日2006-03-21
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
2GFA
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BU of 2gfa by Molmil
double tudor domain complex structure
分子名称: Jumonji domain-containing protein 2A, peptide
著者Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M.
登録日2006-03-21
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
6LNK
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BU of 6lnk by Molmil
Candida albicans Fructose-1,6-bisphosphate aldolase
分子名称: 1,2-ETHANEDIOL, Fructose-bisphosphate aldolase, ZINC ION
著者Huang, Y, Cao, H, Ren, Y, Wan, J.
登録日2019-12-30
公開日2020-12-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.639 Å)
主引用文献Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis.
J.Med.Chem., 65, 2022
3MJ0
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BU of 3mj0 by Molmil
Crystal Structure of Drosophia Ago-PAZ domain in complex with 3'-end 2'-O-methylated RNA
分子名称: Protein argonaute-2, RNA (5'-R(*CP*GP*UP*UP*AP*CP*GP*CP*(OMU))-3')
著者Huang, Y, Ding, L, Ma, J.
登録日2010-04-12
公開日2011-05-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Crystal Structure of drosophila Ago2 PAZ domain in complex with 3'-end 2'-O-methylated RNA
To be Published
8WQ9
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BU of 8wq9 by Molmil
Crystal structure of dihydropyrimidinase complexed with gamma-aminobutyric acid
分子名称: D-hydantoinase/dihydropyrimidinase, GAMMA-AMINO-BUTANOIC ACID, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2023-10-11
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The complexed crystal structure of dihydropyrimidinase reveals a potential interactive link with the neurotransmitter gamma-aminobutyric acid (GABA).
Biochem.Biophys.Res.Commun., 692, 2024
1OMY
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BU of 1omy by Molmil
Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch
分子名称: ACETIC ACID, Alpha-neurotoxin TX12, CHLORIDE ION
著者Huang, Y, Huang, Q, Chen, H, Tang, Y, Miyake, H, Kusunoki, M.
登録日2003-02-26
公開日2003-09-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 59, 2003
6AJD
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BU of 6ajd by Molmil
Crystal structure of a monometallic dihydropyrimidinase from Pseudomonas aeruginosa PAO1 reveals no lysine carbamylation within the active site
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2018-08-27
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.223 Å)
主引用文献Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site
Biochem. Biophys. Res. Commun., 505, 2018
6OMM
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BU of 6omm by Molmil
Cryo-EM structure of formyl peptide receptor 2/lipoxin A4 receptor in complex with Gi
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhuang, Y, Liu, H, de Waal, P.W, Zhou, X.E, Wang, L, Meng, X, Zhao, G, Kang, Y, Melcher, K, Xu, H.E, Zhang, C.
登録日2019-04-19
公開日2020-02-26
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structure of formylpeptide receptor 2-Gicomplex reveals insights into ligand recognition and signaling.
Nat Commun, 11, 2020
8GTD
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BU of 8gtd by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C portal-adaptor complex
分子名称: Head-to-tail joining protein, Portal protein
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTF
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BU of 8gtf by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C stopper-terminator complex
分子名称: Head-to-tail joining protein, Major tail protein, Terminator protein
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTB
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BU of 8gtb by Molmil
Cryo-EM structure of the marine siphophage vB_DshS-R4C tail tube protein
分子名称: Major tail protein
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8GTC
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BU of 8gtc by Molmil
Cryo-EM model of the marine siphophage vB_DshS-R4C baseplate-tail complex
分子名称: Distal tail protein, Hub protein, Major tail protein, ...
著者Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N.
登録日2022-09-08
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
8SRC
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BU of 8src by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ...
著者Huang, Y, Kumar, S, Lu, W, Du, J.
登録日2023-05-05
公開日2024-05-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
8SR7
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BU of 8sr7 by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate
分子名称: 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ...
著者Huang, Y, Kumar, S, Lu, W, Du, J.
登録日2023-05-05
公開日2024-05-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (1.97 Å)
主引用文献Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024

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件を2024-07-17に公開中

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