4EQK
 
 | |
5WJQ
 | | mouseZFP568-ZnF2-11 in complex with DNA | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (28-MER), ZINC ION, ... | | 著者 | Patel, A, Cheng, X. | | 登録日 | 2017-07-24 | | 公開日 | 2018-03-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
|
|
4ENF
 | | Crystal structure of the cap-binding domain of polymerase basic protein 2 from influenza virus A/Puerto Rico/8/34(h1n1) | | 分子名称: | 1,4-BUTANEDIOL, NITRATE ION, Polymerase basic protein 2 | | 著者 | Meng, G, Liu, Y, Zheng, X. | | 登録日 | 2012-04-13 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Structural and functional characterization of K339T substitution identified in the PB2 subunit cap-binding pocket of influenza A virus
J.Biol.Chem., 288, 2013
|
|
3OS5
 | | SET7/9-Dnmt1 K142me1 complex | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Dnmt1, ... | | 著者 | Esteve, P.-O, Chang, Y, Samaranayake, M, Upadhyay, A.K, Horton, J.R, Feehery, G.R, Cheng, X, Pradhan, S. | | 登録日 | 2010-09-08 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.
Nat.Struct.Mol.Biol., 18, 2011
|
|
8MHT
 | | CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX | | 分子名称: | 5'-D(P*CP*CP*AP*TP*GP*UP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... | | 著者 | O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X. | | 登録日 | 1998-08-06 | | 公開日 | 1998-11-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
|
|
5X56
 | |
2FS4
 | | Ketopiperazine-Based Renin Inhibitors: Optimization of the C ring | | 分子名称: | (6R)-6-({[1-(3-HYDROXYPROPYL)-1,7-DIHYDROQUINOLIN-7-YL]OXY}METHYL)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)PIPERAZIN-2-ONE, Renin | | 著者 | Holsworth, D.D, Cai, C, Cheng, X.-M, Cody, W.L, Downing, D.M, Erasga, N, Lee, C, Powell, N.A, Edmunds, J.J, Stier, M, Jalaie, M, Zhang, E, McConnell, P, Ryan, M.J, Bryant, J, Li, T, Kasani, A, Hall, E, Subedi, R, Rahim, M, Maiti, S. | | 登録日 | 2006-01-20 | | 公開日 | 2006-06-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring
BIOORG.MED.CHEM.LETT., 16, 2006
|
|
4ES5
 | |
4EHQ
 | | Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode | | 分子名称: | CALCIUM ION, Calcium release-activated calcium channel protein 1, Calmodulin, ... | | 著者 | Liu, Y, Zheng, X, Mueller, G.A, Sobhany, M, DeRose, E.F, Zhang, Y, London, R.E, Birnbaumer, L. | | 登録日 | 2012-04-03 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9005 Å) | | 主引用文献 | Crystal structure of calmodulin binding domain of orai1 in complex with ca2+*calmodulin displays a unique binding mode.
J.Biol.Chem., 287, 2012
|
|
6K8N
 | | Crystal structure of the Sulfolobus solfataricus topoisomerase III | | 分子名称: | ZINC ION, topoisomerase III | | 著者 | Wang, H.Q, Zhang, J.H, Zheng, X, Zheng, Z.F, Dong, Y.H, Huang, L, Gong, Y. | | 登録日 | 2019-06-13 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of the Sulfolobus solfataricus topoisomerase III reveal that its C-terminal novel zinc finger part is a unique decatenation domain
To Be Published
|
|
6K8O
 | | Crystal structure of the Sulfolobus solfataricus topoisomerase III in complex with DNA | | 分子名称: | DNA (5'-D(*GP*CP*AP*AP*GP*GP*TP*C)-3'), ZINC ION, topoisomerase III | | 著者 | Wang, H.Q, Zhang, J.H, Zheng, X, Zheng, Z.F, Dong, Y.H, Huang, L, Gong, Y. | | 登録日 | 2019-06-13 | | 公開日 | 2020-06-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of the Sulfolobus solfataricus topoisomerase III reveal that its C-terminal novel zinc finger part is a unique decatenation domain
To Be Published
|
|
5JZV
 | | The structure of D77G hCINAP-ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase isoenzyme 6 | | 著者 | Liu, Y, Yang, Z, Yang, Y, Cai, X, Zheng, X. | | 登録日 | 2016-05-17 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth.
Nat Commun, 7, 2016
|
|
8JZL
 | |
8K04
 | | CryoEM structure of a 2,3-hydroxycinnamic acid 1,2-dioxygenase MhpB in apo form | | 分子名称: | 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase | | 著者 | Jiang, W.X, Cheng, X.Q, Ma, L.X, Xing, Q. | | 登録日 | 2023-07-07 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | CryoEM structure of the NADP-dependent malic enzyme in complex with oxaloacetate
To Be Published
|
|
8K0A
 | |
8JZO
 | |
10MH
 | | TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND HEMIMETHYLATED DNA CONTAINING 5,6-DIHYDRO-5-AZACYTOSINE AT THE TARGET | | 分子名称: | DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*5NCP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), ... | | 著者 | Sheikhnejad, G, Brank, A, Christman, J.K, Goddard, A, Alvarez, E, Ford Junior, H, Marquez, V.E, Marasco, C.J, Sufrin, J.R, O'Gara, M, Cheng, X. | | 登録日 | 1998-08-10 | | 公開日 | 1999-02-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.
J.Mol.Biol., 285, 1999
|
|
16VP
 | | CONSERVED CORE OF THE HERPES SIMPLEX VIRUS TRANSCRIPTIONAL REGULATORY PROTEIN VP16 | | 分子名称: | PROTEIN (VP16, VMW65, ATIF), ... | | 著者 | Liu, Y, Gong, W, Huang, C.C, Herr, W, Cheng, X. | | 登録日 | 1999-02-11 | | 公開日 | 1999-07-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16.
Genes Dev., 13, 1999
|
|
5WQA
 | | Crystal structure of PDE4D catalytic domain complexed with Selaginpulvilins K | | 分子名称: | 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde, MAGNESIUM ION, ZINC ION, ... | | 著者 | Huang, Y, Zhang, T, Zheng, X, Yin, S, Luo, H.B. | | 登録日 | 2016-11-24 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata
Biochem. Pharmacol., 130, 2017
|
|
2KW0
 | |
6B0O
 | |
6B0P
 | |
6B0Q
 | |
6B0R
 | |
6MBK
 | | SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, First P212121 Crystal Form | | 分子名称: | 1,2-ETHANEDIOL, Actin peptide, GLYCEROL, ... | | 著者 | Horton, J.R, Dai, S, Cheng, X. | | 登録日 | 2018-08-30 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | SETD3 is an actin histidine methyltransferase that prevents primary dystocia.
Nature, 565, 2019
|
|
