4GQG
 
 | | Crystal structure of AKR1B10 complexed with NADP+ | | 分子名称: | Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zhang, L, Zheng, X, Chen, S, Zhai, J, Hu, X. | | 登録日 | 2012-08-23 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111)
Febs Lett., 587, 2013
|
|
1U2Z
 | | Crystal structure of histone K79 methyltransferase Dot1p from yeast | | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X. | | 登録日 | 2004-07-20 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
J.Biol.Chem., 279, 2004
|
|
4EVV
 | | mouse MBD4 glycosylase domain in complex with a G:T mismatch | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*TP*GP*TP*GP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), ... | | 著者 | Hashimoto, H, Zhang, X, Cheng, X. | | 登録日 | 2012-04-26 | | 公開日 | 2012-07-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation.
Nucleic Acids Res., 40, 2012
|
|
2AOV
 | | Histamine Methyltransferase Complexed with the Antifolate Drug Metoprine | | 分子名称: | 4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE, 5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE-2,4-DIAMINE, Histamine N-methyltransferase | | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | | 登録日 | 2005-08-14 | | 公開日 | 2005-09-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
|
|
3F8J
 | | Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group C222(1) | | 分子名称: | 5'-D(*DCP*DCP*DAP*DTP*DGP*(5CM)P*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(*DGP*DTP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1, ... | | 著者 | Hashimoto, H, Horton, J.R, Zhang, X, Cheng, X. | | 登録日 | 2008-11-12 | | 公開日 | 2009-01-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.
Epigenetics, 4, 2009
|
|
4GZN
 | | Mouse ZFP57 zinc fingers in complex with methylated DNA | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Liu, Y, Zhang, X, Cheng, X. | | 登録日 | 2012-09-06 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | | 主引用文献 | An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence.
Genes Dev., 26, 2012
|
|
3RC0
 | | Human SETD6 in complex with RelA Lys310 peptide | | 分子名称: | 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ... | | 著者 | Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X. | | 登録日 | 2011-03-30 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
|
|
4E12
 | | Substrate-directed dual catalysis of dicarbonyl compounds by diketoreductase | | 分子名称: | Diketoreductase, GLYCEROL, PENTAETHYLENE GLYCOL, ... | | 著者 | Lu, M, White, M.A, Huang, Y, Wu, X, Liu, N, Cheng, X, Chen, Y. | | 登録日 | 2012-03-05 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase
Chem.Commun.(Camb.), 48, 2012
|
|
2HMY
 | | BINARY COMPLEX OF HHAI METHYLTRANSFERASE WITH ADOMET FORMED IN THE PRESENCE OF A SHORT NONPSECIFIC DNA OLIGONUCLEOTIDE | | 分子名称: | PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), S-ADENOSYLMETHIONINE | | 著者 | O'Gara, M, Zhang, X, Roberts, R.J, Cheng, X. | | 登録日 | 1999-02-08 | | 公開日 | 1999-03-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide.
J.Mol.Biol., 287, 1999
|
|
2AOU
 | | Histamine Methyltransferase Complexed with the Antimalarial Drug Amodiaquine | | 分子名称: | 4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL, Histamine N-methyltransferase | | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | | 登録日 | 2005-08-14 | | 公開日 | 2005-09-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
|
|
1XSZ
 | | The structure of RalF | | 分子名称: | guanine nucleotide exchange protein | | 著者 | Amor, J.C, Swails, J, Roy, C.R, Nagai, H, Ingmundson, A, Cheng, X, Kahn, R.A. | | 登録日 | 2004-10-20 | | 公開日 | 2004-11-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site
J.Biol.Chem., 280, 2005
|
|
1XT0
 | | The Structure of N-terminal Sec7 domain of RalF | | 分子名称: | guanine nucleotide exchange protein | | 著者 | Amor, J.C, Swails, J, Roy, C.R, Nagai, H, Ingmundson, A, Cheng, X, Kahn, R.A. | | 登録日 | 2004-10-20 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site
J.Biol.Chem., 280, 2005
|
|
3B95
 | |
8TLL
 | | CDCA7 (Mouse) Binds Non-B-form 26-mer DNA oligo | | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (26-MER), ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
|
|
8TLJ
 | | CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo Containing a 5mC | | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
|
|
8TLK
 | | CDCA7 (Human) Binds Non-B-form 32-mer DNA oligo Containing a 5mC | | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
|
|
8TLE
 | |
8TLF
 | | CDCA7 (Mouse) Binds Non-B-form DNA oligo 36-mer (sg C2-Form 2) | | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, GLYCEROL, ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
|
|
8TLG
 | | CDCA7 (Mouse) Binds Non-B-form 34-mer DNA oligo | | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (34-MER), ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
|
|
8TLH
 | | CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo | | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
|
|
4AY5
 | | Human O-GlcNAc transferase (OGT) in complex with UDP and glycopeptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GTAB1TIDE, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYL TRANSFERASE 110 KDA SUBUNIT, ... | | 著者 | Schimpl, M, Zheng, X, Blair, D.E, Schuettelkopf, A.W, Navratilova, I, Aristotelous, T, Ferenbach, A.T, Macnaughtan, M.A, Borodkin, V.S, van Aalten, D.M.F. | | 登録日 | 2012-06-18 | | 公開日 | 2012-10-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | O-Glcnac Transferase Invokes Nucleotide Sugar Pyrophosphate Participation in Catalysis
Nat.Chem.Biol., 8, 2012
|
|
4JII
 | | Crystal Structure Of AKR1B10 Complexed With NADP+ And Zopolrestat | | 分子名称: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Zhang, L, Zheng, X, Zhang, H, Zhao, Y, Chen, K, Zhai, J, Hu, X, Structural Genomics Consortium (SGC) | | 登録日 | 2013-03-06 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111).
Febs Lett., 587, 2013
|
|
3PTR
 | | PHF2 Jumonji domain | | 分子名称: | 1,2-ETHANEDIOL, PHD finger protein 2 | | 著者 | Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X. | | 登録日 | 2010-12-03 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | | 主引用文献 | Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
|
|
3PUA
 | | PHF2 Jumonji-NOG-Ni(II) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, N-OXALYLGLYCINE, ... | | 著者 | Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X. | | 登録日 | 2010-12-03 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
|
|
1ON9
 | | Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core (with hydrolyzed methylmalonyl-coenzyme a bound) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CADMIUM ION, METHYLMALONYL-COENZYME A, ... | | 著者 | Hall, P.R, Wang, Y.-F, Rivera-Hainaj, R.E, Zheng, X, Pustai-Carey, M, Carey, P.R, Yee, V.C. | | 登録日 | 2003-02-27 | | 公開日 | 2003-05-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core
Embo J., 22, 2003
|
|
