1U2Z

Crystal structure of histone K79 methyltransferase Dot1p from yeast

Summary for 1U2Z

Entry DOI	10.2210/pdb1u2z/pdb
Descriptor	Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
Functional Keywords	histone methyltransferase, nucleosome, transferase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Nucleus: Q04089
Total number of polymer chains	3
Total formula weight	150855.48
Authors	Sawada, K.,Yang, Z.,Horton, J.R.,Collins, R.E.,Zhang, X.,Cheng, X. (deposition date: 2004-07-20, release date: 2004-09-07, Last modification date: 2024-03-13)
Primary citation	Sawada, K.,Yang, Z.,Horton, J.R.,Collins, R.E.,Zhang, X.,Cheng, X. Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase J.Biol.Chem., 279:43296-43306, 2004 Cited by PubMed: 15292170 DOI: 10.1074/jbc.M405902200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation