1U2Z

Crystal structure of histone K79 methyltransferase Dot1p from yeast

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Histone-lysine N-methyltransferase, H3 lysine-79 specific	polymer	433	49900.8	3	UniProt (Q04089) Pfam (PF08123) In PDB	Saccharomyces cerevisiae (baker's yeast)	Histone H3-K79 methyltransferase, H3-K79-HMTase, Disrupter of telomere silencing protein 1
2	A, B, C	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	3	Chemie (SAH)
3		water	water		18.0	533	Chemie (HOH)

Sequence modifications

A, B, C: 158 - 582 (UniProt: Q04089)

PDB	External Database	Details
Met 150	-	expression tag
Gly 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	149702.3
Non-Polymers*	Number of molecules	3
	Total formula weight	1153.2
All*	Total formula weight	150855.5

*Water molecules are not included.