1U2Z
Crystal structure of histone K79 methyltransferase Dot1p from yeast
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone-lysine N-methyltransferase, H3 lysine-79 specific | polymer | 433 | 49900.8 | 3 | UniProt (Q04089) Pfam (PF08123) | Saccharomyces cerevisiae (baker's yeast) | Histone H3-K79 methyltransferase, H3-K79-HMTase, Disrupter of telomere silencing protein 1 |
| 2 | D, E, F (A, B, C) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 3 | Chemie (SAH) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 533 | Chemie (HOH) |
Sequence modifications
A, B, C: 158 - 582 (UniProt: Q04089)
| PDB | External Database | Details |
|---|---|---|
| Met 150 | - | expression tag |
| Gly 151 | - | expression tag |
| His 152 | - | expression tag |
| His 153 | - | expression tag |
| His 154 | - | expression tag |
| His 155 | - | expression tag |
| His 156 | - | expression tag |
| His 157 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 149702.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1153.2 | |
| All* | Total formula weight | 150855.5 |
