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PDB: 1015 results

7VQO
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BU of 7vqo by Molmil
Cryo-EM structure of Ams1 bound to the FW domain of Nbr1
Descriptor: Ams1, Nbr1 and malE fusion protein, ZINC ION
Authors:Zhang, J, Ye, K.
Deposit date:2021-10-20
Release date:2022-07-06
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.19 Å)
Cite:Structural mechanism of protein recognition by the FW domain of autophagy receptor Nbr1
Nat Commun, 13, 2022
6VZO
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BU of 6vzo by Molmil
Crystal structure of human PPARgamma ligand binding domain (Protein delipidated by denature and refold)
Descriptor: Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6VZM
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BU of 6vzm by Molmil
Crystal structure of human PPARgamma ligand binding domain Y473E mutant in complex with Darglitazone
Descriptor: (5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6VZN
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BU of 6vzn by Molmil
Crystal structure of human PPARgamma ligand binding domain Y473E mutant
Descriptor: Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6VZL
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BU of 6vzl by Molmil
Crystal structure of human PPARgamma ligand binding domain in complex with GW1929
Descriptor: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2020-02-28
Release date:2021-03-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural mechanism underlying ligand binding and activation of PPAR gamma.
Structure, 29, 2021
6AVI
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BU of 6avi by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Nonanoic acid
Descriptor: 2-chloro-5-nitro-N-phenylbenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:Shang, J, Kojetin, D.J.
Deposit date:2017-09-02
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6AUG
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BU of 6aug by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with SR16832
Descriptor: 2-chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:Shang, J, Kojetin, D.J.
Deposit date:2017-08-31
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6O67
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BU of 6o67 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Mitoglitazone
Descriptor: Mitoglitazone, Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:Shang, J, Kojetin, D.J.
Deposit date:2019-03-05
Release date:2019-11-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Quantitative structural assessment of graded receptor agonism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6O68
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BU of 6o68 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Ciglitazone
Descriptor: Ciglitazone, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2019-03-05
Release date:2019-11-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Quantitative structural assessment of graded receptor agonism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6DHA
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BU of 6dha by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Hydroxy Pioglitazone (M-IV)
Descriptor: Hydroxy Pioglitazone (M-IV), Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:Shang, J, Mosure, S.A, Kojetin, D.J.
Deposit date:2018-05-18
Release date:2019-03-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPAR gamma Drug Pioglitazone.
J. Med. Chem., 62, 2019
7DDE
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BU of 7dde by Molmil
Cryo-EM structure of the Ape4 and Nbr1 complex
Descriptor: Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION
Authors:Zhang, J, Ye, K.
Deposit date:2020-10-28
Release date:2021-07-14
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
7DD9
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BU of 7dd9 by Molmil
Cryo-EM structure of the Ams1 and Nbr1 complex
Descriptor: Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION
Authors:Zhang, J, Ye, K.
Deposit date:2020-10-28
Release date:2021-07-14
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
6C1I
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BU of 6c1i by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907
Descriptor: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
Authors:Shang, J, Fuhrmann, J, Brust, R, Kojetin, D.J.
Deposit date:2018-01-04
Release date:2018-12-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma.
Nat Commun, 9, 2018
8WYF
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BU of 8wyf by Molmil
Cryo-EM structure of DSR2-DSAD1-NAD+ (partial) complex
Descriptor: Bacillus phage SPbeta DSAD1 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2 family protein
Authors:Zhang, J.T, Jia, N, Liu, X.Y.
Deposit date:2023-10-30
Release date:2024-04-10
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8XG2
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BU of 8xg2 by Molmil
The structure of HLA-A/Pep14
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-14
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
8WY8
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BU of 8wy8 by Molmil
Cryo-EM structure of DSR2 apo complex
Descriptor: SIR2 family protein
Authors:Zhang, J.T, Jia, N, Liu, X.Y.
Deposit date:2023-10-30
Release date:2024-04-10
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8XES
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BU of 8xes by Molmil
The structure of HLA-A/L1-1
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-12
Release date:2024-07-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
6AIX
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BU of 6aix by Molmil
Crystal structure of DXO in complex with adenosine 3', 5' bisphosphate and two magnesium ions
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Decapping and exoribonuclease protein, MAGNESIUM ION
Authors:Chang, J.H, Tong, L.
Deposit date:2018-08-25
Release date:2018-10-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.
Biochem. Biophys. Res. Commun., 504, 2018
6AIY
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BU of 6aiy by Molmil
Crystal structure of DXO (E234A mutant) in complex with adenosine 3', 5' bisphosphate and two magnesium ions
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Decapping and exoribonuclease protein, MAGNESIUM ION
Authors:Chang, J.H, Tong, L.
Deposit date:2018-08-25
Release date:2018-10-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.
Biochem. Biophys. Res. Commun., 504, 2018
7WKJ
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BU of 7wkj by Molmil
A COVID-19 T-cell response detection method based on a newly identified human CD8+ T cell epitope from SARS-CoV-2-Hubei Province, 2021.
Descriptor: Beta-2-microglobulin, LYS-THR-PHE-PRO-PRO-THR-GLU-PRO-LYS, MHC class I antigen
Authors:Zhang, J, Lu, D, Li, M, Liu, M.S, Yao, S.J, Zhan, J.B, Liu, J, Gao, G.F.
Deposit date:2022-01-10
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A COVID-19 T-Cell Response Detection Method Based on a Newly Identified Human CD8 + T Cell Epitope from SARS-CoV-2 - Hubei Province, China, 2021.
China CDC Wkly, 4, 2022
6ONJ
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BU of 6onj by Molmil
Crystal structure of PPARgamma ligand binding domain in complex with TRAP220 peptide and agonist rosiglitazone
Descriptor: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Mediator of RNA polymerase II transcription subunit 1, ...
Authors:Shang, J, Kojetin, D.J.
Deposit date:2019-04-22
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A molecular switch regulating transcriptional repression and activation of PPAR gamma.
Nat Commun, 11, 2020
6ONI
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BU of 6oni by Molmil
Crystal structure of PPARgamma ligand binding domain in complex with N-CoR peptide and inverse agonist T0070907
Descriptor: 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, NCOR isoform c, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2019-04-22
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A molecular switch regulating transcriptional repression and activation of PPAR gamma.
Nat Commun, 11, 2020
7XG3
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BU of 7xg3 by Molmil
CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG0
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BU of 7xg0 by Molmil
CryoEM structure of type IV-A Csf-crRNA-dsDNA ternary complex
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG4
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BU of 7xg4 by Molmil
CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex in a second state
Descriptor: Csf1, Csf2, Csf3, ...
Authors:Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
Deposit date:2022-04-02
Release date:2023-08-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023

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PDB entries from 2024-10-16

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