6VZO
Crystal structure of human PPARgamma ligand binding domain (Protein delipidated by denature and refold)
Summary for 6VZO
| Entry DOI | 10.2210/pdb6vzo/pdb |
| Descriptor | Peroxisome proliferator-activated receptor gamma (2 entities in total) |
| Functional Keywords | nuclear receptors, tzds, drug design, therapeutic targets, transcription |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 62899.04 |
| Authors | Shang, J.,Kojetin, D.J. (deposition date: 2020-02-28, release date: 2021-03-03, Last modification date: 2023-10-11) |
| Primary citation | Shang, J.,Kojetin, D.J. Structural mechanism underlying ligand binding and activation of PPAR gamma. Structure, 29:940-950.e4, 2021 Cited by PubMed: 33713599DOI: 10.1016/j.str.2021.02.006 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
Download full validation report
