6AIY

Crystal structure of DXO (E234A mutant) in complex with adenosine 3', 5' bisphosphate and two magnesium ions

Summary for 6AIY

• Entry DOI: 10.2210/pdb6aiy/pdb
• Related: 6AIX
• Descriptor: Decapping and exoribonuclease protein, ADENOSINE-3'-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: 5'to 3' exoribonuclease, dxo, adenosine 3', 5' bisphosphate, nuclease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 1
• Total formula weight: 43550.31

Authors

Chang, J.H.,Tong, L. (deposition date: 2018-08-25, release date: 2018-10-17, Last modification date: 2022-03-23)

• Primary citation: Yun, J.S.,Yoon, J.H.,Choi, Y.J.,Son, Y.J.,Kim, S.,Tong, L.,Chang, J.H.; Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.; Biochem. Biophys. Res. Commun., 504:89-95, 2018; PubMed: 30180947; DOI: 10.1016/j.bbrc.2018.08.135

Experimental method

X-RAY DIFFRACTION (1.902 Å)