6AIY

Crystal structure of DXO (E234A mutant) in complex with adenosine 3', 5' bisphosphate and two magnesium ions

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Decapping and exoribonuclease protein	polymer	378	43074.5	1	UniProt (O70348) Pfam (PF08652)	Mus musculus (Mouse)	DXO,Dom-3 homolog Z
2	B (A)	ADENOSINE-3'-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (A3P)
3	C, D (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	E (A)	water	water		18.0	262	Chemie (HOH)

Sequence modifications

A: 27 - 384 (UniProt: O70348)

PDB	External Database	Details
Met 7	-	expression tag
Gly 8	-	expression tag
Ser 9	-	expression tag
Ser 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Ser 17	-	expression tag
Ser 18	-	expression tag
Gly 19	-	expression tag
Leu 20	-	expression tag
Val 21	-	expression tag
Pro 22	-	expression tag
Arg 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
His 26	-	expression tag
Ala 234	Glu 234	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43074.5
Non-Polymers*	Number of molecules	3
	Total formula weight	475.8
All*	Total formula weight	43550.3

*Water molecules are not included.