5YCP
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![BU of 5ycp by Molmil](/molmil-images/mine/5ycp) | Human PPARgamma ligand binding domain complexed with Rosiglitazone | Descriptor: | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Nuclear receptor coactivator 1, ... | Authors: | Jang, J.Y, Han, B.W. | Deposit date: | 2017-09-07 | Release date: | 2018-09-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Enhanced Anti-Diabetic Efficacy of Lobeglitazone on PPAR gamma. Sci Rep, 8, 2018
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6A0H
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6A0F
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5XIX
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![BU of 5xix by Molmil](/molmil-images/mine/5xix) | The canonical domain of human asparaginyl-tRNA synthetase | Descriptor: | Asparagine--tRNA ligase, cytoplasmic, GLYCEROL | Authors: | Park, J.S, Han, B.W. | Deposit date: | 2017-04-28 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity. Int. J. Biol. Macromol., 120, 2018
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6A0I
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6A0E
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4FYB
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![BU of 4fyb by Molmil](/molmil-images/mine/4fyb) | Structural and functional characterizations of a thioredoxin-fold protein from Helicobacter pylori | Descriptor: | GLYCEROL, Thiol:disulfide interchange protein (DsbC) | Authors: | Yoon, J.Y, Kim, J, Lee, S.J, Im, H.N, Kim, H.S, Yoon, H, An, D.R, Kim, J.Y, Kim, S, Han, B.W, Suh, S.W. | Deposit date: | 2012-07-04 | Release date: | 2013-05-08 | Last modified: | 2013-09-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and functional characterization of HP0377, a thioredoxin-fold protein from Helicobacter pylori Acta Crystallogr.,Sect.D, 69, 2013
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4J15
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![BU of 4j15 by Molmil](/molmil-images/mine/4j15) | Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex | Descriptor: | Aspartate--tRNA ligase, cytoplasmic, GLYCEROL | Authors: | Kim, K.R, Park, S.H, Kim, H.S, Kim, B.-G, Kim, D.G, Rhee, K.H, Park, M.S, Kim, H.-J, Kim, S, Han, B.W. | Deposit date: | 2013-02-01 | Release date: | 2013-05-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex Proteins, 81, 2013
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4GSQ
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![BU of 4gsq by Molmil](/molmil-images/mine/4gsq) | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains | Descriptor: | CALCIUM ION, GLYCEROL, Probable conserved lipoprotein LPPS | Authors: | Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W. | Deposit date: | 2012-08-28 | Release date: | 2013-02-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains Acta Crystallogr.,Sect.D, 69, 2013
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4GSR
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![BU of 4gsr by Molmil](/molmil-images/mine/4gsr) | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains | Descriptor: | 2-(ETHYLMERCURI-THIO)-BENZOIC ACID, GLYCEROL, Probable conserved lipoprotein LPPS | Authors: | Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W. | Deposit date: | 2012-08-28 | Release date: | 2013-02-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains Acta Crystallogr.,Sect.D, 69, 2013
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6IJR
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![BU of 6ijr by Molmil](/molmil-images/mine/6ijr) | Human PPARgamma ligand binding domain complexed with SB1495 | Descriptor: | 16 mer peptide from Nuclear receptor coactivator 1, N-{[3-({[(1S,2R)-2-{[(2E)-2-cyano-4,4-dimethylpent-2-enoyl]amino}cyclopentyl]oxy}methyl)phenyl]methyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamide, Peroxisome proliferator-activated receptor gamma | Authors: | Jang, J.Y, Han, B.W. | Deposit date: | 2018-10-11 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation. Sci Rep, 9, 2019
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6IY6
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![BU of 6iy6 by Molmil](/molmil-images/mine/6iy6) | Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS) | Descriptor: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Aspartate--tRNA ligase, cytoplasmic, ... | Authors: | Park, S.H, Hahn, H, Han, B.W. | Deposit date: | 2018-12-13 | Release date: | 2019-09-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex. Iucrj, 6, 2019
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6JQ7
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7WWP
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![BU of 7wwp by Molmil](/molmil-images/mine/7wwp) | Crystal structure of human Npl4 | Descriptor: | Nuclear protein localization protein 4 homolog, ZINC ION | Authors: | Nguyen, T.Q, Le, L.T.M, Kim, D.H, Ko, K.S, Lee, H.T, Nguyen, Y.T.K, Kim, H.S, Han, B.W, Kang, W, Yang, J.K. | Deposit date: | 2022-02-14 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1. Structure, 30, 2022
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7WWQ
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![BU of 7wwq by Molmil](/molmil-images/mine/7wwq) | Crystal structure of human Ufd1-Npl4 complex | Descriptor: | Nuclear protein localization protein 4 homolog, Ubiquitin recognition factor in ER-associated degradation protein 1 | Authors: | Nguyen, T.Q, Le, L.T.M, Kim, D.H, Ko, K.S, Lee, H.T, Nguyen, Y.T.K, Kim, H.S, Han, B.W, Kang, W, Yang, J.K. | Deposit date: | 2022-02-14 | Release date: | 2022-09-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1. Structure, 30, 2022
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6IJS
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![BU of 6ijs by Molmil](/molmil-images/mine/6ijs) | Human PPARgamma ligand binding domain complexed with SB1494 | Descriptor: | 16-mer peptide from Nuclear receptor coactivator 1, N-{[3-({[(1R,2S)-2-{[(2E)-2-cyano-4,4-dimethylpent-2-enoyl]amino}cyclopentyl]oxy}methyl)phenyl]methyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamide, Peroxisome proliferator-activated receptor gamma | Authors: | Jang, J.Y, Han, B.W. | Deposit date: | 2018-10-11 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation. Sci Rep, 9, 2019
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6K95
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6KTN
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![BU of 6ktn by Molmil](/molmil-images/mine/6ktn) | Human PPARgamma ligand-binding domain R288A mutant in complex with imatinib | Descriptor: | 16-mer peptide from Nuclear receptor coactivator 1, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Peroxisome proliferator-activated receptor gamma | Authors: | Jang, J.Y, Han, B.W. | Deposit date: | 2019-08-28 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.752 Å) | Cite: | Structural Basis for the Regulation of PPAR gamma Activity by Imatinib. Molecules, 24, 2019
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6KY1
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6KTM
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6K8C
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6KY0
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6L89
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![BU of 6l89 by Molmil](/molmil-images/mine/6l89) | Human PPARgamma ligand binding domain complexed with Butyrolactone 1 | Descriptor: | Peroxisome proliferator-activated receptor gamma, methyl (2R)-3-(4-hydroxyphenyl)-2-[[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]methyl]-4-oxidanyl-5-oxidanylidene-furan-2-carboxylate | Authors: | Jang, D.M, Han, B.W. | Deposit date: | 2019-11-05 | Release date: | 2020-09-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cyclin-Dependent Kinase 5 Inhibitor Butyrolactone I Elicits a Partial Agonist Activity of Peroxisome Proliferator-Activated Receptor gamma. Biomolecules, 10, 2020
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6L4G
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2BDU
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![BU of 2bdu by Molmil](/molmil-images/mine/2bdu) | X-Ray Structure of a Cytosolic 5'-Nucleotidase III from Mus Musculus MM.158936 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cytosolic 5'-nucleotidase III | Authors: | Wesenberg, G.E, Phillips Jr, G.N, Han, B.W, Bitto, E, Bingman, C.A, Bae, E, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2005-10-20 | Release date: | 2005-11-01 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
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