6IY6

Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS)

Summary for 6IY6

Entry DOI	10.2210/pdb6iy6/pdb
Descriptor	Aspartate--tRNA ligase, cytoplasmic, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Bifunctional glutamate/proline--tRNA ligase, ... (6 entities in total)
Functional Keywords	aminoacyl-trna transferase glutathion-s transferase domain, translation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	401385.13
Authors	Park, S.H.,Hahn, H.,Han, B.W. (deposition date: 2018-12-13, release date: 2019-09-11, Last modification date: 2023-11-22)
Primary citation	Hahn, H.,Park, S.H.,Kim, H.J.,Kim, S.,Han, B.W. The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex. Iucrj, 6:958-967, 2019 Cited by PubMed: 31576228 DOI: 10.1107/S2052252519010790 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation