7WWQ

Crystal structure of human Ufd1-Npl4 complex

Summary for 7WWQ

Entry DOI	10.2210/pdb7wwq/pdb
Descriptor	Nuclear protein localization protein 4 homolog, Ubiquitin recognition factor in ER-associated degradation protein 1 (3 entities in total)
Functional Keywords	p97, ufd1, npl4, edoplasmid reticulum-associated degradation, ubiquitin, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	54755.72
Authors	Nguyen, T.Q.,Le, L.T.M.,Kim, D.H.,Ko, K.S.,Lee, H.T.,Nguyen, Y.T.K.,Kim, H.S.,Han, B.W.,Kang, W.,Yang, J.K. (deposition date: 2022-02-14, release date: 2022-09-21, Last modification date: 2022-11-16)
Primary citation	Nguyen, T.Q.,My Le, L.T.,Kim, D.H.,Ko, K.S.,Lee, H.T.,Kim Nguyen, Y.T.,Kim, H.S.,Han, B.W.,Kang, W.,Yang, J.K. Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1. Structure, 30:1530-1537.e3, 2022 Cited by PubMed: 36087575 DOI: 10.1016/j.str.2022.08.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.72 Å)

Structure validation