5YCP
Human PPARgamma ligand binding domain complexed with Rosiglitazone
Summary for 5YCP
Entry DOI | 10.2210/pdb5ycp/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, Nuclear receptor coactivator 1, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... (4 entities in total) |
Functional Keywords | ppargamma, agonist, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 34542.96 |
Authors | Jang, J.Y.,Han, B.W. (deposition date: 2017-09-07, release date: 2018-09-12, Last modification date: 2023-11-22) |
Primary citation | Jang, J.Y.,Bae, H.,Lee, Y.J.,Choi, Y.I.,Kim, H.J.,Park, S.B.,Suh, S.W.,Kim, S.W.,Han, B.W. Structural Basis for the Enhanced Anti-Diabetic Efficacy of Lobeglitazone on PPAR gamma. Sci Rep, 8:31-31, 2018 Cited by PubMed: 29311579DOI: 10.1038/s41598-017-18274-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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