5YCP
Human PPARgamma ligand binding domain complexed with Rosiglitazone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 283 | 32280.3 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | B (B) | Nuclear receptor coactivator 1 | polymer | 16 | 1905.2 | 1 | UniProt (Q15788) | Homo sapiens | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
3 | C (A) | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL) | non-polymer | 357.4 | 1 | Chemie (BRL) | |||
4 | D, E (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34185.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 357.4 | |
All* | Total formula weight | 34543.0 |