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5YCP

Human PPARgamma ligand binding domain complexed with Rosiglitazone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APeroxisome proliferator-activated receptor gammapolymer28332280.31UniProt (P37231)
Pfam (PF00104)
In PDB
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2BNuclear receptor coactivator 1polymer161905.21UniProt (Q15788)
In PDB
Homo sapiensNCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1
3A2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL)non-polymer357.41Chemie (BRL)
4waterwater18.085Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34185.5
Non-Polymers*Number of molecules1
Total formula weight357.4
All*Total formula weight34543.0
*Water molecules are not included.

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PDB entries from 2024-04-24

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