6KTM
The ligand-free structure of human PPARgamma ligand-binding domain R288A mutant in the presence of the SRC-1 coactivator peptide
Summary for 6KTM
Entry DOI | 10.2210/pdb6ktm/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, 16-mer peptide from Nuclear receptor coactivator 1 (3 entities in total) |
Functional Keywords | type 2 diabetes mellitus, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 34099.42 |
Authors | Jang, J.Y.,Han, B.W. (deposition date: 2019-08-28, release date: 2020-02-05, Last modification date: 2023-11-22) |
Primary citation | Jang, J.Y.,Kim, H.J.,Han, B.W. Structural Basis for the Regulation of PPAR gamma Activity by Imatinib. Molecules, 24:-, 2019 Cited by PubMed: 31581474DOI: 10.3390/molecules24193562 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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