6KTM

The ligand-free structure of human PPARgamma ligand-binding domain R288A mutant in the presence of the SRC-1 coactivator peptide

Summary for 6KTM

Entry DOI	10.2210/pdb6ktm/pdb
Descriptor	Peroxisome proliferator-activated receptor gamma, 16-mer peptide from Nuclear receptor coactivator 1 (3 entities in total)
Functional Keywords	type 2 diabetes mellitus, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	34099.42
Authors	Jang, J.Y.,Han, B.W. (deposition date: 2019-08-28, release date: 2020-02-05, Last modification date: 2023-11-22)
Primary citation	Jang, J.Y.,Kim, H.J.,Han, B.W. Structural Basis for the Regulation of PPAR gamma Activity by Imatinib. Molecules, 24:-, 2019 Cited by PubMed: 31581474 DOI: 10.3390/molecules24193562 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation