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6JQ7

The ligand-free structure of human PPARgamma LBD in the presence of the SRC-1 coactivator peptide

Summary for 6JQ7
Entry DOI10.2210/pdb6jq7/pdb
DescriptorPeroxisome proliferator-activated receptor gamma, 16-mer peptide from Nuclear receptor coactivator 1 (3 entities in total)
Functional Keywordsppargamma, agonist, transcription
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight34185.54
Authors
Jang, J.Y.,Han, B.W. (deposition date: 2019-03-29, release date: 2019-10-16, Last modification date: 2023-11-22)
Primary citationJang, J.Y.,Kim, H.,Kim, H.J.,Suh, S.W.,Park, S.B.,Han, B.W.
Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation.
Sci Rep, 9:11168-11168, 2019
Cited by
PubMed: 31371757
DOI: 10.1038/s41598-019-47672-w
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

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