6JQ7
The ligand-free structure of human PPARgamma LBD in the presence of the SRC-1 coactivator peptide
Summary for 6JQ7
Entry DOI | 10.2210/pdb6jq7/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, 16-mer peptide from Nuclear receptor coactivator 1 (3 entities in total) |
Functional Keywords | ppargamma, agonist, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 34185.54 |
Authors | Jang, J.Y.,Han, B.W. (deposition date: 2019-03-29, release date: 2019-10-16, Last modification date: 2023-11-22) |
Primary citation | Jang, J.Y.,Kim, H.,Kim, H.J.,Suh, S.W.,Park, S.B.,Han, B.W. Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation. Sci Rep, 9:11168-11168, 2019 Cited by PubMed: 31371757DOI: 10.1038/s41598-019-47672-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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