6JQ7

The ligand-free structure of human PPARgamma LBD in the presence of the SRC-1 coactivator peptide

Summary for 6JQ7

• Entry DOI: 10.2210/pdb6jq7/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, 16-mer peptide from Nuclear receptor coactivator 1 (3 entities in total)
• Functional Keywords: ppargamma, agonist, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 34185.54

Authors

Jang, J.Y.,Han, B.W. (deposition date: 2019-03-29, release date: 2019-10-16, Last modification date: 2023-11-22)

• Primary citation: Jang, J.Y.,Kim, H.,Kim, H.J.,Suh, S.W.,Park, S.B.,Han, B.W.; Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation.; Sci Rep, 9:11168-11168, 2019; PubMed: 31371757; DOI: 10.1038/s41598-019-47672-w

Experimental method

X-RAY DIFFRACTION (2.55 Å)