3RCO
 
 | | Crystal structure of a conserved motif in human TDRD7 | | 分子名称: | CHLORIDE ION, Tudor domain-containing protein 7 | | 著者 | Dong, A, Xu, C, Walker, J.R, Lam, R, Guo, Y, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2011-03-31 | | 公開日 | 2012-04-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a conserved motif in human TDRD7
To be Published
|
|
6BAJ
 | |
6MOI
 | | Dimeric DARPin C_angle_R5 complex with EpoR | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dimeric DARPing CCR5 (C_angle_R5), ... | | 著者 | Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y. | | 登録日 | 2018-10-04 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.065 Å) | | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
|
|
6MOK
 | | Dimeric DARPin A_distance_R7 complex with EpoR | | 分子名称: | Dimeric DARPin ANR7 (A_distance_r7), Erythropoietin receptor | | 著者 | Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y. | | 登録日 | 2018-10-04 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (5.101 Å) | | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
|
|
3O8V
 | | Crystal Structure of the Tudor Domains from FXR1 | | 分子名称: | Fragile X mental retardation syndrome-related protein 1 | | 著者 | Lam, R, Guo, Y.H, Adams-Cioaba, M, Bian, C.B, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2010-08-03 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2.
Plos One, 5, 2010
|
|
6MOL
 | | Monoextended DARPin M_R12 complex with EpoR | | 分子名称: | Erythropoietin receptor, GLYCEROL, Monoextended DARPin R12 (M_R12) | | 著者 | Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y. | | 登録日 | 2018-10-04 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.163 Å) | | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
|
|
2OY0
 | | Crystal structure of the West Nile virus methyltransferase | | 分子名称: | Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Li, H.M, Zhao, Y.W, Guo, Y, Shi, P.Y. | | 登録日 | 2007-02-21 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure and Function of Flavivirus NS5 Methyltransferase.
J.Virol., 81, 2007
|
|
7DMY
 | | The crystal structure of Cpd7 in complex with BPTF bromodomain | | 分子名称: | Nucleosome-remodeling factor subunit BPTF, tert-butyl 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-4-oxidanylidene-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate | | 著者 | Xiong, L, Guo, Y, Yang, S. | | 登録日 | 2020-12-08 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization.
Biochem.Biophys.Res.Commun., 545, 2021
|
|
7DN4
 | | The crystal structure of Cpd8 in complex with BPTF bromodomain | | 分子名称: | 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-one, Nucleosome-remodeling factor subunit BPTF | | 著者 | Xiong, L, Guo, Y, Yang, S. | | 登録日 | 2020-12-08 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.841 Å) | | 主引用文献 | Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization.
Biochem.Biophys.Res.Commun., 545, 2021
|
|
6CSX
 | |
4RQF
 | | human Seryl-tRNA synthetase dimer complexed with one molecule of tRNAsec | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE, Serine--tRNA ligase, ... | | 著者 | Xie, W, Wang, C, Guo, Y, Tian, Q, Jia, Q. | | 登録日 | 2014-11-03 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | | 主引用文献 | SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Nucleic Acids Res., 43, 2015
|
|
2OJE
 | | Mycoplasma arthritidis-derived mitogen complexed with class II MHC molecule HLA-DR1/HA complex in the presence of EDTA | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain precursor, DRB1-1 beta chain precursor, ... | | 著者 | Li, H, Zhao, Y, Guo, Y, Li, Z, Eisele, L, Mourad, W. | | 登録日 | 2007-01-12 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.
J.Biol.Chem., 282, 2007
|
|
4RQE
 | | human Seryl-tRNA synthetase dimer complexed with two molecules of tRNAsec | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE, Serine--tRNA ligase, ... | | 著者 | Xie, W, Wang, C, Guo, Y, Tian, Q, Jia, Q. | | 登録日 | 2014-11-03 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Nucleic Acids Res., 43, 2015
|
|
2AXJ
 | | Crystal structures of T cell receptor beta chains related to rheumatoid arthritis | | 分子名称: | SF4 T cell receptor beta chain | | 著者 | Li, H, Van Vranken, S, Zhao, Y, Li, Z, Guo, Y, Eisele, L, Li, Y. | | 登録日 | 2005-09-05 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
|
|
2AXH
 | | Crystal structures of T cell receptor beta chains related to rheumatoid arthritis | | 分子名称: | T cell receptor beta chain | | 著者 | Li, H, Van Vranken, S, Zhao, Y, Li, Z, Guo, Y, Eisele, L, Li, Y. | | 登録日 | 2005-09-05 | | 公開日 | 2005-09-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
|
|
8WNT
 | | Cryo EM map of SLC7A10 with L-Alanine substrate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ... | | 著者 | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | 登録日 | 2023-10-06 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
|
|
2N17
 | | NMR structure of a Kazal-type serine protease inhibitor from the subterranean termite defense gland of Coptotermes formosanus Shiraki soldiers | | 分子名称: | Lysozyme-Protease Inhibitor Protein | | 著者 | Negulescu, H, Guo, Y, Garner, T.P, Goodwin, O.Y, Henderson, G, Laine, R.A, Macnaughtan, M.A. | | 登録日 | 2015-03-23 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki.
Plos One, 10, 2015
|
|
3W2D
 | | Crystal Structure of Staphylococcal Eenterotoxin B in complex with a novel neutralization monoclonal antibody Fab fragment | | 分子名称: | Enterotoxin type B, Monoclonal Antibody 3E2 Fab figment heavy chain, Monoclonal Antibody 3E2 Fab figment light chain, ... | | 著者 | Liang, S.Y, Hu, S, Dai, J.X, Guo, Y.J, Lou, Z.Y. | | 登録日 | 2012-11-28 | | 公開日 | 2013-12-25 | | 最終更新日 | 2014-04-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site.
MAbs, 6, 2014
|
|
3WLW
 | | Molecular Architecture of the ErbB2 Extracellular Domain Homodimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody H Chain, ... | | 著者 | Hu, S, Lou, Z.Y, Guo, Y.J. | | 登録日 | 2013-11-15 | | 公開日 | 2015-05-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.088 Å) | | 主引用文献 | Molecular architecture of the ErbB2 extracellular domain homodimer.
Oncotarget, 6, 2015
|
|
3ED0
 | | Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin | | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, BENZAMIDINE, ... | | 著者 | Zhang, L, Zhang, H, Liu, W, Guo, Y, Shen, X, Jiang, H. | | 登録日 | 2008-09-02 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
BMC MICROBIOL., 9, 2009
|
|
8WNY
 | | Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ... | | 著者 | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | 登録日 | 2023-10-06 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
|
|
8WNS
 | | Cryo EM map of SLC7A10 in the apo state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1 | | 著者 | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | 登録日 | 2023-10-06 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
|
|
5BTU
 | |
5BU3
 | | Crystal Structure of Diels-Alderase PyrI4 in complex with its product | | 分子名称: | (4S,4aS,6aS,8R,9R,10aR,13R,14aS,18aR,18bR)-9-ethyl-4,8,19-trihydroxy-10a,12,13,18a-tetramethyl-2,3,4,4a,5,6,6a,7,8,9,10,10a,13,14,18a,18b-hexadecahydro-1H-14a,17-(metheno)benzo[b]naphtho[2,1-h]azacyclododecine-16,18(15H,17H)-dione, GLYCEROL, PyrI4 | | 著者 | Pan, L, Guo, Y, Liu, J. | | 登録日 | 2015-06-03 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | | 主引用文献 | Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4
Cell Chem Biol, 23, 2016
|
|
5DYS
 | | Crystal Structure of T94I rhodopsin mutant | | 分子名称: | ACETATE ION, PALMITIC ACID, RETINAL, ... | | 著者 | Singhal, A, Guo, Y, Matkovic, M, Schertler, G, Deupi, X, Yan, E, Standfuss, J. | | 登録日 | 2015-09-25 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural role of the T94I rhodopsin mutation in congenital stationary night blindness.
Embo Rep., 17, 2016
|
|
