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3ED0

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin

Summary for 3ED0
Entry DOI10.2210/pdb3ed0/pdb
Related2GLL
Descriptor(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsfabz complex, emodin, cytoplasm, lipid a biosynthesis, lipid synthesis, lyase
Biological sourceHelicobacter pylori
Cellular locationCytoplasm (By similarity): Q5G940
Total number of polymer chains6
Total formula weight110830.97
Authors
Zhang, L.,Zhang, H.,Liu, W.,Guo, Y.,Shen, X.,Jiang, H. (deposition date: 2008-09-02, release date: 2009-07-21, Last modification date: 2023-11-01)
Primary citationChen, J.,Zhang, L.,Zhang, Y.,Zhang, H.,Du, J.,Ding, J.,Guo, Y.,Jiang, H.,Shen, X.
Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
BMC MICROBIOL., 9:91-91, 2009
Cited by
PubMed: 19433000
DOI: 10.1186/1471-2180-9-91
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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