3EWF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ewf by Molmil](/molmil-images/mine/3ewf) | Crystal Structure Analysis of human HDAC8 H143A variant complexed with substrate. | 分子名称: | 7-AMINO-4-METHYL-CHROMEN-2-ONE, Histone deacetylase 8, PEPTIDIC SUBSTRATE, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-14 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
|
|
3EZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezt by Molmil](/molmil-images/mine/3ezt) | Crystal Structure Analysis of Human HDAC8 D101E Variant | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-23 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
|
|
3F07
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f07 by Molmil](/molmil-images/mine/3f07) | Crystal Structure Analysis of Human HDAC8 complexed with APHA in a new monoclinic crystal form | 分子名称: | (2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide, Histone deacetylase 8, POTASSIUM ION, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-24 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
|
|
3EZP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezp by Molmil](/molmil-images/mine/3ezp) | Crystal Structure Analysis of human HDAC8 D101N variant | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-23 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
|
|
3F0R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f0r by Molmil](/molmil-images/mine/3f0r) | Crystal Structure Analysis of Human HDAC8 complexed with trichostatin A in a new monoclinic crystal form | 分子名称: | Histone deacetylase 8, POTASSIUM ION, TRICHOSTATIN A, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-25 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
|
|
3EW8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ew8 by Molmil](/molmil-images/mine/3ew8) | Crystal Structure Analysis of human HDAC8 D101L variant | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, GLYCEROL, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-14 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
|
|
3F06
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f06 by Molmil](/molmil-images/mine/3f06) | Crystal Structure Analysis of Human HDAC8 D101A Variant. | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-24 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
|
|
5AZ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5az2 by Molmil](/molmil-images/mine/5az2) | Crystal structure of the Fab fragment of 9E5, a murine monoclonal antibody specific for human epiregulin | 分子名称: | anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain | 著者 | Kado, Y, Mizohata, E, Nagatoishi, S, Iijima, M, Shinoda, K, Miyafusa, T, Nakayama, T, Yoshizumi, T, Sugiyama, A, Kawamura, T, Lee, Y.H, Matsumura, H, Doi, H, Fujitani, H, Kodama, T, Shibasaki, Y, Tsumoto, K, Inoue, T. | 登録日 | 2015-09-16 | 公開日 | 2015-12-09 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (1.603 Å) | 主引用文献 | Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES J.Biol.Chem., 291, 2016
|
|
6XF9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xf9 by Molmil](/molmil-images/mine/6xf9) | Crystal structure of KSHV ORF68 | 分子名称: | Packaging protein UL32, ZINC ION | 著者 | Didychuk, A.L, Gates, S.N, Martin, A, Glaunsinger, B. | 登録日 | 2020-06-15 | 公開日 | 2021-02-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | A pentameric protein ring with novel architecture is required for herpesviral packaging. Elife, 10, 2021
|
|
6XFA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xfa by Molmil](/molmil-images/mine/6xfa) | Cryo-EM structure of EBV BFLF1 | 分子名称: | Packaging protein UL32, ZINC ION | 著者 | Didychuk, A.L, Gates, S.N, Martin, A, Glaunsinger, B. | 登録日 | 2020-06-15 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | A pentameric protein ring with novel architecture is required for herpesviral packaging. Elife, 10, 2021
|
|
5E8D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e8d by Molmil](/molmil-images/mine/5e8d) | Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5 | 分子名称: | CHLORIDE ION, GLYCEROL, Proepiregulin, ... | 著者 | Kado, Y, Mizohata, E, Nagatoishi, S, Iijima, M, Shinoda, K, Miyafusa, T, Nakayama, T, Yoshizumi, T, Sugiyama, A, Kawamura, T, Lee, Y.H, Matsumura, H, Doi, H, Fujitani, H, Kodama, T, Shibasaki, Y, Tsumoto, K, Inoue, T. | 登録日 | 2015-10-14 | 公開日 | 2015-12-09 | 最終更新日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES J.Biol.Chem., 291, 2016
|
|
1RZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rz8 by Molmil](/molmil-images/mine/1rz8) | CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B | 分子名称: | Fab 17b heavy chain, Fab 17b light chain | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | 登録日 | 2003-12-24 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1RZK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rzk by Molmil](/molmil-images/mine/1rzk) | HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | 登録日 | 2003-12-24 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
4YRD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yrd by Molmil](/molmil-images/mine/4yrd) | Crystal structure of CapF with inhibitor 3-isopropenyl-tropolone | 分子名称: | 2-hydroxy-3-(prop-1-en-2-yl)cyclohepta-2,4,6-trien-1-one, Capsular polysaccharide synthesis enzyme Cap5F, ZINC ION | 著者 | Nakano, K, Chigira, T, Miyafusa, T, Nagatoishi, S, Caaveiro, J.M.M, Tsumoto, K. | 登録日 | 2015-03-15 | 公開日 | 2015-10-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus. Sci Rep, 5, 2015
|
|
1RZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rz7 by Molmil](/molmil-images/mine/1rz7) | CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 48D | 分子名称: | Fab 48d heavy chain, Fab 48d light chain, GLYCEROL | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | 登録日 | 2003-12-24 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1RZI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rzi by Molmil](/molmil-images/mine/1rzi) | Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab | 分子名称: | Fab 47e heavy chain, Fab 47e light chain | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | 登録日 | 2003-12-24 | 公開日 | 2004-02-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1RZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rzf by Molmil](/molmil-images/mine/1rzf) | Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51 | 分子名称: | Fab E51 heavy chain, Fab E51 light chain, GLYCEROL, ... | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | 登録日 | 2003-12-24 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
3MZ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mz3 by Molmil](/molmil-images/mine/3mz3) | Crystal structure of Co2+ HDAC8 complexed with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, COBALT (II) ION, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2010-05-11 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
|
|
3MZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mz4 by Molmil](/molmil-images/mine/3mz4) | Crystal structure of D101L Mn2+ HDAC8 complexed with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2010-05-11 | 公開日 | 2010-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.845 Å) | 主引用文献 | Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
|
|
3MZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mz6 by Molmil](/molmil-images/mine/3mz6) | Crystal structure of D101L Fe2+ HDAC8 complexed with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, FE (II) ION, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2010-05-11 | 公開日 | 2010-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
|
|
3MZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mz7 by Molmil](/molmil-images/mine/3mz7) | Crystal structure of D101L Co2+ HDAC8 complexed with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, COBALT (II) ION, GLYCEROL, ... | 著者 | Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2010-05-11 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
|
|
1RZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rzg by Molmil](/molmil-images/mine/1rzg) | Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d | 分子名称: | ASPARTIC ACID, CYSTEINE, Fab 412d heavy chain, ... | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | 登録日 | 2003-12-24 | 公開日 | 2004-02-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1RZJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rzj by Molmil](/molmil-images/mine/1rzj) | HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | 登録日 | 2003-12-24 | 公開日 | 2004-02-03 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
5Y78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y78 by Molmil](/molmil-images/mine/5y78) | Crystal structure of the triose-phosphate/phosphate translocator in complex with inorganic phosphate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PHOSPHATE ION, Putative hexose phosphate translocator | 著者 | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | 登録日 | 2017-08-16 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
|
|
5Y79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y79 by Molmil](/molmil-images/mine/5y79) | Crystal structure of the triose-phosphate/phosphate translocator in complex with 3-phosphoglycerate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-PHOSPHOGLYCERIC ACID, CITRATE ANION, ... | 著者 | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | 登録日 | 2017-08-16 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
|
|