1RZF

Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51

Summary for 1RZF
Related1RZ7 1RZ8 1RZG 1RZI 1RZJ 1RZK
DescriptorFab E51 light chain, Fab E51 heavy chain, GLYCEROL, ... (5 entities in total)
Functional Keywordshiv-1; gp120; cd4i; antibodies; tyrosine sulfation; vh-gene usage, immune system
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total formula weight48401.50
Authors
Primary citationChoe, H.,Dimitrov, D.S.,Farzan, M.,Hendrickson, W.A.,Huang, C.C.,Kwong, P.D.,Majeed, S.,Moore, M.J.,Phogat, S.,Robinson, J.,Sodroski, J.,Venturi, M.,Wyatt, R.,Zhang, M.-Y.
Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101:2706-2711, 2004
PubMed: 14981267
DOI: 110.1073/pnas.0308527100
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation
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PDB entries from 2021-06-09