1RZF

Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 9001

Chain	Residue
H	LYS209
L	ALA113
L	HIS198
L	SER201
L	HOH9050
L	HOH9054
L	HOH9154

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 9002

Chain	Residue
L	PRO59
L	ARG61
L	PHE62
L	GLY81
L	ASP82
L	GLN37
L	LYS45

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL L 9003

Chain	Residue
H	THR183
L	SER115
L	THR117
L	LEU136
L	ILE137
L	SER138

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site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 9004

Chain	Residue
L	THR105
L	VAL106
L	LEU107
L	GLY108
L	GLN109
L	LYS111
L	PRO142

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 9005

Chain	Residue
L	ALA144
L	VAL145
L	THR146
L	THR197
L	GLU199
L	GLY200
L	HOH9061

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site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL L 9010

Chain	Residue
H	SER172
L	ARG54
L	PRO55
L	SER56
L	GLY57
L	ILE58
L	GLY159
L	VAL160
L	GLU161
L	HOH9159

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL L 9011

Chain	Residue
L	PRO110
L	TYR141
L	ASN171
L	HOH9067

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site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 9012

Chain	Residue
H	ILE53
L	SER65
L	LYS66
L	SER67
L	SER70
L	ALA71
L	THR72

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 9013

Chain	Residue
H	PHE54
L	LYS18
L	THR20
L	SER63
L	GLY64
L	SER65
L	HOH9106

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA L 7001

Chain	Residue
L	GLN38
L	GLY41

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site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IPA L 7002

Chain	Residue
H	GLN43
H	GLY44
L	ASP85
L	TYR87
L	GLY100

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site_id	BC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL H 9006

Chain	Residue
H	GLY100
H	TYR100
H	ASP100
H	HOH9020
L	ASP32
L	SER34
L	TYR36
L	GLY89
L	THR90
L	VAL96

---

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 9007

Chain	Residue
H	SER120
H	VAL121
H	LYS209
H	HOH9166
L	SER201
L	VAL203
L	HOH9054

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 9008

Chain	Residue
H	ARG38
H	GLN39
H	ALA40
H	GLN43
H	GLY44
H	GLU46
H	HOH9062

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 9009

Chain	Residue
H	LEU45
H	GLU46
H	HOH9010
H	HOH9014
H	HOH9108

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR194-HIS200

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