3CD4
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2A91
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![BU of 2a91 by Molmil](/molmil-images/mine/2a91) | Crystal structure of ErbB2 domains 1-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-2 | Authors: | Garrett, T.P.J, McKern, N.M, Lou, M, Elleman, T.C, Adams, T.E, Lovrecz, G.O, Kofler, M, Jorissen, R.N, Nice, E.C, Burgess, A.W. | Deposit date: | 2005-07-11 | Release date: | 2005-07-26 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors Mol.Cell, 11, 2003
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1MOX
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![BU of 1mox by Molmil](/molmil-images/mine/1mox) | Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Garrett, T.P.J, McKern, N.M, Lou, M, Elleman, T.C, Adams, T.E, Lovrecz, G.O, Zhu, H.-J, Walker, F, Frenkel, M.J, Hoyne, P.A, Jorissen, R.N, Nice, E.C, Burgess, A.W, Ward, C.W. | Deposit date: | 2002-09-10 | Release date: | 2003-09-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor alpha Cell(Cambridge,Mass.), 110, 2002
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3G5X
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3G5V
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![BU of 3g5v by Molmil](/molmil-images/mine/3g5v) | Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR | Descriptor: | 806 light chain, 808 heavy chain, ACETATE ION, ... | Authors: | Garrett, T.P.J, Burgess, A.W, Huyton, T, Xu, Y. | Deposit date: | 2009-02-05 | Release date: | 2010-02-09 | Last modified: | 2011-10-12 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106, 2009
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3G5Y
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3G5Z
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1IGR
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![BU of 1igr by Molmil](/molmil-images/mine/1igr) | Type 1 Insulin-like growth factor receptor (DOMAINS 1-3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, INSULIN-LIKE GROWTH FACTOR RECEPTOR 1, ... | Authors: | Garrett, T.P.J, Mckern, N.M, Lou, M, Frenkel, M.J, Bentley, J.D, Lovrecz, G.O, Elleman, T.C, Cosgrove, L.J, Ward, C.W. | Deposit date: | 1998-09-28 | Release date: | 1999-09-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor. Nature, 394, 1998
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1GHS
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2HLA
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2HR7
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![BU of 2hr7 by Molmil](/molmil-images/mine/2hr7) | Insulin receptor (domains 1-3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Garrett, T.P.J, Ward, C.W. | Deposit date: | 2006-07-19 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2PCY
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3L5I
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![BU of 3l5i by Molmil](/molmil-images/mine/3l5i) | Crystal structure of FnIII domains of human GP130 (Domains 4-6) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Interleukin-6 receptor subunit beta | Authors: | Kershaw, N.J, Zhang, J.-G, Garrett, T.P.J, Czabotar, P.E. | Deposit date: | 2009-12-22 | Release date: | 2010-05-12 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285, 2010
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3L5J
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![BU of 3l5j by Molmil](/molmil-images/mine/3l5j) | Crystal structure of FnIII domains of human GP130 (Domains 4-6) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Interleukin-6 receptor subunit beta | Authors: | Kershaw, N.J, Zhang, J.-G, Garrett, T.P.J, Czabotar, P.E. | Deposit date: | 2009-12-22 | Release date: | 2010-05-12 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.042 Å) | Cite: | Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285, 2010
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1MOE
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![BU of 1moe by Molmil](/molmil-images/mine/1moe) | The three-dimensional structure of an engineered scFv T84.66 dimer or diabody in VL to VH linkage. | Descriptor: | SULFATE ION, anti-CEA mAb T84.66 | Authors: | Carmichael, J.A, Power, B.E, Garrett, T.P.J, Yazaki, P.J, Shively, J.E, Raubischek, A.A, Wu, A.M, Hudson, P.J. | Deposit date: | 2002-09-09 | Release date: | 2003-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Crystal Structure of an Anti-CEA scFv Diabody Assembled from T84.66 scFvs in VL-to-VH Orientation: Implications for Diabody Flexibility J.Mol.Biol., 326, 2003
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3L5H
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![BU of 3l5h by Molmil](/molmil-images/mine/3l5h) | Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6 receptor subunit beta, SULFATE ION, ... | Authors: | Xu, Y, Garrett, T.P.J, Zhang, J.G. | Deposit date: | 2009-12-21 | Release date: | 2010-05-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285, 2010
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2B8H
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![BU of 2b8h by Molmil](/molmil-images/mine/2b8h) | A/NWS/whale/Maine/1/84 (H1N9) reassortant influenza virus neuraminidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Smith, B.J, Platis, D, Cox, M.M.J, Huyton, T, Joosten, R.P, McKimm-Breschkin, J.L, Zhang, J.-G, Luo, C.S, Lou, M.-Z, Garrett, T.P.J, Labrou, N.E. | Deposit date: | 2005-10-07 | Release date: | 2006-09-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding. Acta Crystallogr.,Sect.D, 62, 2006
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1GHR
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2Q7N
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![BU of 2q7n by Molmil](/molmil-images/mine/2q7n) | Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Huyton, T, Zhang, J.G, Nicola, N.A, Garrett, T.P.J. | Deposit date: | 2007-06-07 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor. Proc.Natl.Acad.Sci.USA, 104, 2007
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