3L5I

Crystal structure of FnIII domains of human GP130 (Domains 4-6)

Summary for 3L5I

Entry DOI	10.2210/pdb3l5i/pdb
Related	3L5H 3L5J
Descriptor	Interleukin-6 receptor subunit beta, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	cytokine receptor, fibronectin type iii domain, cell membrane, disulfide bond, immunoglobulin domain, membrane, receptor, secreted, transmembrane, immune system
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Secreted : P40189
Total number of polymer chains	1
Total formula weight	34247.27
Authors	Kershaw, N.J.,Zhang, J.-G.,Garrett, T.P.J.,Czabotar, P.E. (deposition date: 2009-12-22, release date: 2010-05-12, Last modification date: 2017-11-01)
Primary citation	Xu, Y.,Kershaw, N.J.,Luo, C.S.,Soo, P.,Pocock, M.J.,Czabotar, P.E.,Hilton, D.J.,Nicola, N.A.,Garrett, T.P.,Zhang, J.G. Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285:21214-21218, 2010 Cited by PubMed: 20489211 DOI: 10.1074/jbc.C110.129502 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation