1MOX

Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha

Summary for 1MOX
Related1IGR 1M6B 2TGF
DescriptorEpidermal Growth Factor Receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming Growth Factor alpha, ... (11 entities in total)
Functional Keywordsegfr, receptor, complex, growth factor, transferase-growth factor complex, transferase/growth factor
Biological sourceHomo sapiens (human)
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Total number of polymer chains4
Total formula weight127948.54
Authors
Primary citationAdams, T.E.,Burgess, A.W.,Elleman, T.C.,Frenkel, M.J.,Garrett, T.P.J.,Hoyne, P.A.,Jorissen, R.N.,Lou, M.,Lovrecz, G.O.,McKern, N.M.,Nice, E.C.,Walker, F.,Ward, C.W.,Zhu, H.-J.
Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor alpha
Cell(Cambridge,Mass.), 110:763-773, 2002
PubMed: 12297049
DOI: 110.1016/S0092-8674(02)00940-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation
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PDB entries from 2021-06-16