2A91
| Crystal structure of ErbB2 domains 1-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-2 | Authors: | Garrett, T.P.J, McKern, N.M, Lou, M, Elleman, T.C, Adams, T.E, Lovrecz, G.O, Kofler, M, Jorissen, R.N, Nice, E.C, Burgess, A.W. | Deposit date: | 2005-07-11 | Release date: | 2005-07-26 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors Mol.Cell, 11, 2003
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1MOX
| Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Garrett, T.P.J, McKern, N.M, Lou, M, Elleman, T.C, Adams, T.E, Lovrecz, G.O, Zhu, H.-J, Walker, F, Frenkel, M.J, Hoyne, P.A, Jorissen, R.N, Nice, E.C, Burgess, A.W, Ward, C.W. | Deposit date: | 2002-09-10 | Release date: | 2003-09-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor alpha Cell(Cambridge,Mass.), 110, 2002
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1A3P
| ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES | Descriptor: | EPIDERMAL GROWTH FACTOR | Authors: | Barnham, K, Torres, A, Alewood, D, Alewood, P, Domagala, T, Nice, E, Norton, R. | Deposit date: | 1998-01-22 | Release date: | 1998-07-29 | Last modified: | 2018-03-14 | Method: | SOLUTION NMR | Cite: | Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor. Protein Sci., 7, 1998
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3EGF
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1EGF
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1IQ1
| CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX | Descriptor: | IMPORTIN ALPHA-2 SUBUNIT | Authors: | Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B. | Deposit date: | 2001-05-28 | Release date: | 2001-11-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Biophysical characterization of interactions involving importin-alpha during nuclear import. J.Biol.Chem., 276, 2001
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3G5X
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3G5V
| Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR | Descriptor: | 806 light chain, 808 heavy chain, ACETATE ION, ... | Authors: | Garrett, T.P.J, Burgess, A.W, Huyton, T, Xu, Y. | Deposit date: | 2009-02-05 | Release date: | 2010-02-09 | Last modified: | 2011-10-12 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Proc.Natl.Acad.Sci.USA, 106, 2009
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3G5Y
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3G5Z
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1PJN
| Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex | Descriptor: | Histone-binding protein N1/N2, Importin alpha-2 subunit | Authors: | Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. | Deposit date: | 2003-06-03 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
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1PJM
| Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex | Descriptor: | Importin alpha-2 subunit, Retinoblastoma-associated protein | Authors: | Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B. | Deposit date: | 2003-06-03 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha J.Biol.Chem., 278, 2003
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