2A91

Crystal structure of ErbB2 domains 1-3

Summary for 2A91

• Entry DOI: 10.2210/pdb2a91/pdb
• Descriptor: Receptor tyrosine-protein kinase erbB-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: tyrosine kinase receptor; cell-surface receptor, signaling protein, transferase, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 57860.27

Authors

Garrett, T.P.J.,McKern, N.M.,Lou, M.,Elleman, T.C.,Adams, T.E.,Lovrecz, G.O.,Kofler, M.,Jorissen, R.N.,Nice, E.C.,Burgess, A.W. (deposition date: 2005-07-11, release date: 2005-07-26, Last modification date: 2022-12-21)

• Primary citation: Garrett, T.P.J.,McKern, N.M.,Lou, M.,Elleman, T.C.,Adams, T.E.,Lovrecz, G.O.,Kofler, M.,Jorissen, R.N.,Nice, E.C.,Burgess, A.W.; The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors; Mol.Cell, 11:495-505, 2003; PubMed: 12620236; DOI: 10.1016/S1097-2765(03)00048-0

Experimental method

X-RAY DIFFRACTION (2.5 Å)