2A91
Crystal structure of ErbB2 domains 1-3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Receptor tyrosine-protein kinase erbB-2 | polymer | 517 | 56993.5 | 1 | UniProt (P04626) Pfam (PF01030) Pfam (PF00757) In PDB | Homo sapiens (human) | p185erbB2; C-erbB-2; NEU proto-oncogene; Tyrosine kinase-type cell surface receptor HER2; MLN 19 |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 1 - 509 (UniProt: P04626)
| PDB | External Database | Details |
|---|---|---|
| Lys 309 | Arg 330 | conflict |
| Lys 496 | Arg 517 | conflict |
| Asp 510 | - | expression tag |
| Tyr 511 | - | expression tag |
| Lys 512 | - | expression tag |
| Asp 513 | - | expression tag |
| Asp 514 | - | expression tag |
| Asp 515 | - | expression tag |
| Asp 516 | - | expression tag |
| Lys 517 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56993.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 57860.3 |
