1MOX

Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Epidermal Growth Factor Receptor	polymer	501	55693.3	2	UniProt (P00533) Pfam (PF01030) Pfam (PF00757) In PDB	Homo sapiens (human)
2	C, D	Transforming Growth Factor alpha	polymer	50	5560.2	2	UniProt (P01135) In PDB	Homo sapiens (human)
3	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
4	F	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
5	G	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
6	H	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
7	A, B	PLATINUM (II) ION	non-polymer		195.1	7	Chemie (PT)
8	B, C, D, A	CADMIUM ION	non-polymer		112.4	11	Chemie (CD)
9	B, A	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
10	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
11		water	water		18.0	79	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	122507.1
Branched	Number of molecules	4
	Total formula weight	2476.3
Non-Polymers*	Number of molecules	23
	Total formula weight	2965.1
All*	Total formula weight	127948.5

*Water molecules are not included.