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2HR7

Insulin receptor (domains 1-3)

Summary for 2HR7
Entry DOI10.2210/pdb2hr7/pdb
DescriptorInsulin receptor, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, ... (12 entities in total)
Functional Keywordshormone receptor, leucine rich repeat, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight122958.43
Authors
Garrett, T.P.J.,Ward, C.W. (deposition date: 2006-07-19, release date: 2006-08-15, Last modification date: 2023-08-30)
Primary citationLou, M.,Garrett, T.P.,McKern, N.M.,Hoyne, P.A.,Epa, V.C.,Bentley, J.D.,Lovrecz, G.O.,Cosgrove, L.J.,Frenkel, M.J.,Ward, C.W.
The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity.
Proc.Natl.Acad.Sci.Usa, 103:12429-12434, 2006
Cited by
PubMed: 16894147
DOI: 10.1073/pnas.0605395103
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.32 Å)
Structure validation

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